Is cannabis good for Crohn's ?

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be been told by a lot of people that weed is good to help releave the sypomtoms of crohns
But I've found when I've taken it it just has not worked well at all
I've cooked with it
Made tea with it
Taken it in pill form
The first few times it made me tired but not help the pain I have
I've got a volcanic vaporiser to try it that way
I'm sick of been told to take all these tablets I'm like a walking pill !
I no that white and purple strains of weed is the best to take but its had no effects on me
When I was younger I use to smoke a load of it but I don't wanna go back to doing that I don't want to get high I want pain relief
Has any body found different ways to use it which I have not tried !
 
Hello Kiki, welcome to the MJ forum! :)

The scientific literature on the efficacy of medical cannabis in treating IBD is currently very convincing. Even prestigious journals like the JAMA are publishing studies on the medicinal capabilities of cannabis. Ever since it was discovered the cannabinoid cannabidiol (CBD) could bind to CB2 receptors in our body (around 2008 if memory serves, which is recent all things considered), MJ started getting a lot more credibility and recognition. This discovery has spawned specialized teams of cannabis geneticists (mostly in Spain and the Netherlands) that have been conducting research on CBD. Nowadays, it is possible to buy CBD-rich strains (as much as 10% CBD content) of MJ.

There are many ways to prepare medical cannabis and unless you prepare it correctly, you will not get to experience all the benefits. So let's analyze how you did it before and maybe try something new so you can get some relief.

Tea = no good at all. Cannabinoids (delta9-THC and CBD, the two of most interest to you) are liposoluble, which means they bind with molecules of fat. They cannot bind to water at all, so if you make tea with cannabis, you are essentially wasting almost all of it, because the medicine will never be metabolized in your body after ingestion.

Pill. Pills that are well prepared should provide some effect. Were the pills self-made, or prescribed by a doctor? Pills like Idrasil do work and and they do exist.

Cooking. To cook with cannabis you must first extract the cannabinoids into a fat, then use that fat to cook. Butter is the best fat to use for extraction. The process is simple, and there are a few methods you can try. I will soon be sharing a picture tutorial on how to prepare cannabutter, so if this is of interest to you, check back here this week-end and it should be up.

Vaporizing is by far, the most practical way to medicate (edibles are more efficient but require a lot more work). If you have a Volcano, you can use it with very small amounts of herb (0.1-0.3g) at a middle heat setting. Take slow and deep inhalation, then exhale immediately. It is a myth that holding the vapor inside your lungs for a long time will accentuate the effects. Research has shown that passed the first two seconds of contact between the bronchioles and the vapor, there is less than 2% exchange, so you're just damaging your lungs for no benefit at all by withholding smoke or vapor inside.

The quality of your medicine will also affect the outcome. Marijuana that was harvested before it was ripe and ready will not be potent enough to make a difference. If it wasn't cured properly after harvest, it might also not be as efficient.

To check whether your medicine is of quality, grab a piece of flower (bud) and squeeze it between your thumb and index finger. The bud should be dry and dense. Not airy or humid. Afterwards, inspect it visually. It should be covered by a fine whitish powder. It may be difficult to see with the naked eye if you have vision problems, so using a loupe to inspect your medicine is always easier. The white powdery substance are dried up trichromes, which are the structures of the plant that produces all the cannabinoids we want. If your flower is airy, wet or does not present that white surface, you are in possession of a subpar product and you should ask for your money back.

I hope this helps you!
 
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Solid info right there!


On a personal level, Yes, I have noticed some relief using cannabis. I take 2-3 hits of a vaporizer and within a few min, I can get that modest amount of relief.

I've only recently began experimenting with it to find that sweet spot, but I very much beleive there is a place for cannabis in helping those of us affected with Crohns/UC.
 
You should save the vaped remains from your volcano... you can cook with them! Just be sure they are finely ground. I shared my really simple recipe in this thread. It's a good beginner's method of cooking with cannabis.
 
I have definitely noticed less symptoms with Marijuana use. Actually, I recently was in "remission" and went on vacation. I wasn't worried about having a supply with me since I had been doing so well and by the end of my trip (without weed) I began having cramping, nausea and overall just not feeling well again.

I think weed not only helps alleviate symptoms as they are happening, but I think it has an effect on the gut that can help with inflammation for days also. I have researched some on this and found some studies that seem to back this up, but I am in no way able to repeat all the jargon. haha. Either way I am sticking to it. I would rather try more natural things that adding any more pharm drugs to my list!
 
I think weed not only helps alleviate symptoms as they are happening, but I think it has an effect on the gut that can help with inflammation for days also. !

You are correct Myriah. Marijuana actually has the power to treat the inflammatory cascade via CB2 receptors action. Our body naturally produces a good number of cannabinoids (though they are different than the ones produces by the cannabis plant) and they all have a role to play in regulating our gut and inflammatory processes.

There are actually many studies now that have confirmed THC and CBD reduce inflammation. What remains to be elucidated is how effective they are (quantified somehow according to a system the researchers would come up with) and how long-lasting the effects may be. Unfortunately, this information came to light only very recently (2008-2009 or so) and it seems many people, including those in the scientific community, are not keeping themselves up to date with the latest literature. Even publications like the JAMA are publishing cannabis studies now, so things are changing.

It may take years before the tools and funding to measure the performance of marijuana on an empirical scale are acquired, but there is no doubt a lot of research is being done on marijuana nowadays.

We can can expect a lot of interesting papers to be published in the next decade.
 
How about Cannabis tinctures, FrancisK7? You mention that tea is useless and that this has to do with Cannabis being insoluble. But I suffer with Crohns of the ileum and was very lucky to be given a few drops of tincture recently. To my amazement the pain and discomfort vanished and for six or more days I felt definite improvement. Maybe the tincture is a kind of oil, though you take it with water? I really think there is some benefit in this.
 
Tinctures work because they are oil-based and oil is a fat, so the cannabinoids will bind to the oil, making tinctures a worthy delivery method for the medicine.
 
Aha, thanks. I thought that this must be the case. The tincture drops are oil and putting them into a little water probably helps them to travel down the throat and not sting the mouth Anyway I'm impressed and definitely see medicinal value for my Crohns symptoms.
 
The thing about the Tincture I was given is that it didn't seem to stone me much at all. I have nothing against the interesting mental affects of cannabis but in my case if I were to be in a position to use the tincture as a regular medicine for my Crohns I would need it not to stone me much but still to be effective in the ati-inflamatory and painkilling areas. I have no idea which strain was in my tincture but it would be very helpful to know which strains are considered most effective for Crohns in tincture form. Anyone feel like suggesting some?
 
The thing about the Tincture I was given is that it didn't seem to stone me much at all. I have nothing against the interesting mental affects of cannabis but in my case if I were to be in a position to use the tincture as a regular medicine for my Crohns I would need it not to stone me much but still to be effective in the ati-inflamatory and painkilling areas. I have no idea which strain was in my tincture but it would be very helpful to know which strains are considered most effective for Crohns in tincture form. Anyone feel like suggesting some?

The thing with edibles or tinctures is that they are metabolized directly into the gut, which limits interactions with the brain receptors. Whereas when you inhale vapor or smoke, it first goes through your lungs, where it is then assimilated into the bloodstream and goes everywhere, eventually finding the CB1 and CB2 receptors both in your brain and gut.

The tincture that goes through your stomach will therefore be prioritized by your bowel receptors, and will be metabolized much more slowly, creating a more localized effect.

Less brain involvement = less of a head high, more of a body high (meaning more pain relief and body relaxation than a couch-lock or euphoric effect).

Different strains will also affect people differently. It's not fully understood how, but the ratios of the different cannabinoids present in the plant make a difference.
 
Yes, thanks Francis. This is really helpful and informative..

So my small amount of tincture may still be based on a fairly potent plant? From the point of view of being able to work or just wake up easily in the morning I was pleasantly surprised. Because the positive medicinal pain-killing effect on my gut was really noticable, but the high wasn't.

This is much more useful and subtle than Codeine,.which is what my doctor tends to give if Iam in pain. But I an frankly amazed at how effective this tincture has been. It has been days since I used it and it has had a more positive effect than even Infliximab/Remicade. And though this might be a plecebo response I would expect a plecebo to fail to be effective after a while. Both times I have tried this it has gone a long way towards mending my guts for days.

I had a large amount of terminal ileum removed in 2003 and ever since have lived with ...loose bowel movements. This is a daily grind that Infliximab only slows down a bit. But the tincture has simply removed the loose movements from the equation It has also removed soreness around my abdomen and made my digestive system cope amazingly well with food. It was my birthday yesterday and I pushed things further than usual by earing various bits of cake and cheese, various things that would usually cause me some grief. But there was no grief. I'm convinced the tincture has not just helped with pain but done something else to regulate my guts. I keep on finding myself thinking 'where's the catch?' But there doesn't seem to be one.
 
Tinctures are great, you can actually sooth the gut w them, probably more so than via inhalation, iv been wanting to get some oil or make some cannabutter but it's too expensive so i just use the vaporizer and that works a treat for me
 
I think i'm going to have to look into making some tinctures or some drop based cannabis oil.
 
So my small amount of tincture may still be based on a fairly potent plant?

Absolutely! It will depend on how the tincture was prepared of course, but tinctures work as well as edibles. In fact, they probably work a little better, but they're not as enjoyable as a brownie ;)

It was my birthday yesterday

Happy birthday! :dance:


I keep on finding myself thinking 'where's the catch?' But there doesn't seem to be one.

Cannabis has its downsides. There's more than enough data to prove cannabis can aggravate mental illnesses or even bring its onset in predisposed individuals. This is one of the major catch.

Otherwise, cannabis is extremely safe. It cannot kill and is not addictive, two properties many LEGAL drugs have.

We can't proclaim cannabis is without its problems but compared to the benefits they are almost irrelevant.

I am 100% sure that as soon as we can produce a potent strain of marijuana that is not psychoactive (CBD is not psychoactive at all but it requires some THC be present to be properly modulated, so it's not as simple as producing a strain with 0% THC content and maximum CBD content) cannabis will be a standard treatment option for IBD, just like 5-ASA are.

Cannabis was MADE for people with IBD. The bulk of our CB1 and CB2 receptors are in our brain and our gut. It's a match made in heaven!
 
I think i'm going to have to look into making some tinctures or some drop based cannabis oil.

It's very easy to make tinctures.

You can buy a small bottle with a dropper at the pharmacy for 1 or 2$. Use the crackpot method in my cannabrownie post, but substitute butter for olive oil.

I usually vaporize 0.1g per bowl with a vaporizer. I find it to be an effective maintenance dose if taken 2-3 times a day at regular interval.

To prepare half a cup of tincture (125ml), simply put 125ml of olive oil in the crockpot, and grind 5 to 7g of cannabis, and let it simmer overnight on low. Assuming a drop equals 1-3ml, every drop would equal a 0.04g-.12g dose. Start there and see how it goes. You can adjust the number of drops according to your symptoms.
 
It's very easy to make tinctures.

You can buy a small bottle with a dropper at the pharmacy for 1 or 2$. Use the crackpot method in my cannabrownie post, but substitute butter for olive oil.

I saw crackpot and was like :eek2: lol

Thanks for all the great info francis. I was wondering why my cannabis tea made me sick....
 
I know marijuana is effective for treating the symptoms and pain of Crohn's, but does it actually help the colon heal itself or help reduce inflammation in any way?

I would like to smoke medical marijuana, but am concerned the smoke inhalation effects would cause more inflammation? I'm sure edibles/vaporizing would minimize this problem, but are there any inflammatory effects at all that marijuana might cause?

Lastly, does anyone know of a good website to get credible studies about medical marijuana?
 
I would like to know the answers to these questions too. There are lots of articles from different sources you can find by searching the internet and many would seem to have been written by medical researchers. And certainly the case for cannabis as an effective pain killer and appetite stimulant has been strong enough for drugs companies to develop products based on it. One reads about its anti-inflamatory properties too and because it seems to be a powerful anti-oxidant some people have said it can protect against Cancer. I did find this article interesting:

http://www.ncbi.nlm.nih.gov/pubmed/1650492

Because if I am not wrong, Infliximab or Remicade which are front line medicines in treating Crohns disease do something to TNF alpha in order to inhibit the inflamation of the gut. Is seems THC or THA have some action in this regard.


Enough noise has been made about it for me to have tried cannabis for my Crohns. My experience was that the tincture I tried was extraordinarily good at reducing discomfort in my small intestine, and not just reducing pain but settling my entire gut for days when I had previously been suffering ongoing diarrohea. It reduced the psychological aggrivation too and helped me to sleep. In terms of stoning me, it just didn't, which leads me to speculate that it may have been low THC with a greater proportion of CBD. Pity I can't get more of this stuff. Vaporising was the other experiment and whilst this too seemed to calm my intestines the strain I tried was too strong in the wrong way. From that unsettling experience i have concluded that Medical Grade would be the safer bet for me and in tincture form. As for causing inflammation I do very much doubt that Cannabis would do this. I used a very cheap and basic vaporiser and the hot vapour was a little uncomfortable on my throat but its effect on the intestines is really benevolent.
 
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I know marijuana is effective for treating the symptoms and pain of Crohn's, but does it actually help the colon heal itself or help reduce inflammation in any way?

I would like to smoke medical marijuana, but am concerned the smoke inhalation effects would cause more inflammation? I'm sure edibles/vaporizing would minimize this problem, but are there any inflammatory effects at all that marijuana might cause?

Lastly, does anyone know of a good website to get credible studies about medical marijuana?

Hi Smack,

To answer your first question, cannabis does treat inflammation via our CB2 receptors, so it does treat Crohn's and UC in a small fashion. The anti-inflammatory properties of cannabis are however not as potent as that of specialized drugs like mesalamine. So while cannabis taken alone is highly unlikely to treat the disease on its own, it will definitely land a helping hand.

Smoking would not increase inflammation any more than edibles or vaporizing would. If it would have any effect on inflammation, it would decrease it. You are more susceptible to lung irritation (which isn't the same as inflammation) because of the smoke though, which can be harsh. If you'd like to use cannabis medicinally a vaporizer is a great investment.

Here is a list of studies for you to read.
 
Thank you so much Francis for your 'list of studies'. It is great documentation for my crohns Dr at his request. he keeps on top of crohns biology, will appreciate the literature, and discuss further with me. As my physician we have discussed my choice to try this therapy, both old school and 1Tbsp hemp oil daily (yuk yuk yuk!). Time will tell since there is mild stricture and active crohns now. Great read since I am home post op incisional hernia surgery now. fml they found 2 holes haha!
 
Hey Nicle2a5, welcome to the CG forums :)

I'm so happy to hear about your communication with your doctor. That is a GREAT relationship you have. Make sure you keep this GI at all costs :) It's actually pretty rare to find doctors who are open to dialog with their patients, and who will be receptive to other therapies that are introduced to them via unusual channels (aka not medschool or a conference organized by the board of their specialty or a pharmaceutical)/

If you're looking to cannabis as a therapy, ingestion is, by far, the best delivery method. You could make your own oils and tinctures that are much more effective than hemp oil.

Raw cannabis is also something to look for. There have been a few reports on raw cannabis therapy, which consists of using a juice extractor to juice the leaves of a cannabis plant still in its vegetation cycle. The main advantage is that when you do this, THC, CBD, CBG, CBN and the other cannabinoids are delivered in your system in their acid form, which is not psychoactive (it doesn't get you high, at all). This allows people to take doses that are much bigger than you otherwise could via inhalation (some folks juice an entire plant each day, getting as much as 600 mg doses in a single glass of cannabis juice). It's extremely acid and doesn't taste good AT ALL, but you can mix it up with your favorite fruit juice and drink it that way. I've seen folks grow 30 plants they keep in veg, and juice one plant a day, each month. You'd need a masticating juicer (not centrifugal) to go that route, and they're expensive, but I'm currently considering this way of using cannabis right now.

There have been reports of people using raw cannabis or CBD oil to put their UC or Crohn's into remission after everything else has failed. The experimental science DOES support the idea that cannabinoids are capable or reducing inflammation, regulating transit, gut activity, etc. CBD has even been shown to kill cancer cells in vitro, but we're still a long way from declaring cannabis the cure of all problems.

If you can try cannabis therapy, I do suggest you try it. Especially if your state has medical legislation that makes access easy.
 
why isn't hemp oil as effective as tincture or homemade oil? aren't cb1/2 affected as much? No MM isnt allowed (yet).
Tammy
 
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