Looks like it could be genetic after all

[MunMun]

Aloha, Hallo, Hey!

Long time no see lol. Before you continue reading i want you to smile, not like but i mean big smile!

I sincerely hope you are all coping with your conditions and i hope even more that your mental state is as healthy as an apple ( or InsertWord ) lol.

I'm yet to be seen, i've got my examination on the 27th Feb hopefully, NHS waiting lists are longgg. But anyway, my younger sister today told me she had blood in her stool and that it's been on going. Then i asked mum and she said the same, that it's been regular. An even my 12year old once had the whole toilet full of blood and then on an off ever since.

Could this possibly mean that it's something genetic and runs in the family? Does blood in the stool always constitute some sort of IBS? An they don't mean it's a one off blood but regular blood.

I'm thinking BINGO! It's genetic after all, or maybe i could be wrong. Diabetes runs in family but IBS isn't as clear. They don't think it's serious enough to have it checked out.

 

[Rebecca85]

I think you might have IBS and IBD confused. IBS is a functional problem, meaning no physical damage can be seen to the intestines. IBD is inflammatory bowel disease, where the intestines become inflamed and can lead to blood in the stool.

Blood in the stool may not mean IBD, but it is a red flag symptom that needs investigating, as it could be from something as simple as hemmies, or as serious as cancer, so please get your family members to get checked out if they aren't already!

 

[kem53]

Crohn's disease and Ulcerative Colitis can run in families. My mother has Ulcerative Colitis, I have indeterminate colitis and my daughter has Crohn's. As Rebecca stated, blood in the stool does warrant a doctor visit. I hope everyone is well and it is just a false alarm, but it is better to be safe than sorry!

 

[heameljon]

Crohn's Disease and UC are genetic. You inherit a recessive gene from both your parents. The mutation is located on the Nod2, if you google Nod2 and Crohn's disease you will find many articles. Here is one link:

http://www.sciencemag.org/content/307/5710/734.short

An old doctor of mine had 6 family members with Crohn's, and he told me that it is not uncommon to have a family member with Crohn's and one with UC. I have CD and several years later a cousin was diagnosed with UC.

I hope your sister goes and gets things checked out and everything is OK. And I hope they find nothing to be wrong.

 

[Rebecca85]

It's not as simple as that, there are many genes thought to be implicated in IBD inheritance. IBD1 has been identified as well as NOD2. If it were only 1 gene, then family inheritance would be much more straightforward- more like the pattern for cystic fibrosis, say.

 

[MunMun]

I'm all new to this so i don't know the names that well.

It became a suprise to me when they told me this. But will hopefully let the doc know when i go see them. I'm worried about my mum mainly coz she's older and it could be more.

I dunno about my father, but i can try an ask about it. 'Hey, paps do you bleed when you go toilet' lol, not exactly the polite way to go about it. But hey we see

 

[heameljon]

It's not as simple as that, there are many genes thought to be implicated in IBD inheritance. IBD1 has been identified as well as NOD2. If it were only 1 gene, then family inheritance would be much more straightforward- more like the pattern for cystic fibrosis, say.

I wasn't trying to imply simplicity, just trying to give a quick explanation. It is most certainly inherited and I understand the complexity of the factors involved.

 

[Miss Underestimated]

People can have the genetic defect, but not have the disease. I know in my case, something had to have triggered it - if there had been no "trigger" the disease would have remained dormant.

 

[tlc-x]

We have Crohn's and UC in the family on my dads side. It definately runs in my family! Almost all of us on that side of the family have it.