Entocort does work and is a great maintenance drug for crohns located in the terminal ileum. If you doctor wont prescribe it, find a new doctor and talk to them about all the options. Prednisone is NOT a maintenance drug and should only be used during acute flares to get them under control and then the taper required after. If your doctor wants you on prednisone as maintenance, then that is not a doctor I would want. However, if you are in a flare and she is saying it doesn't work to knock a flare down, then that is ok since the prednisone does in fact work much better than pretty much every other drug on the market for dealing with a flare rapidly.