New AGA Guideline for Diet and Nutritional Therapies for IBD

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Scipio

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The AGA has issued new GI practice guidelines for diet and nutritional therapies for IBD:

The Guideline:

https://www.gastrojournal.org/action/showPdf?pii=S0016-5085(23)05597-X

Summary:

A Starting Point

First, the panelists advise that, unless contraindicated, all patients with IBD follow a Mediterranean diet while minimizing salt, sugar, and ultraprocessed foods.

Patients with symptomatic intestinal strictures may struggle to digest raw fruits and vegetables due to their fibrous nature, they added, so these patients should first soften these foods through cooking, steaming, or "careful chewing" before consumption.

"No diet has consistently been found to decrease the rate of flares in adults with IBD," the update panelists noted. "A diet low in red and processed meat may reduce ulcerative colitis flares, but has not been found to reduce relapse in Crohn's disease."

Beyond these dietary suggestions for adults, the update advises breastfeeding for newborns and a Mediterranean diet for children, as both may reduce risk of developing IBD.


Enteral Nutrition

The update suggests that exclusive enteral nutrition is a reasonable option to induce clinical remission and endoscopic response, or as a steroid-sparing bridge, in Crohn's disease, although this may be more effective in children than adults.

Malnourished patients may also benefit from exclusive enteral nutrition prior to elective surgery for Crohn's disease, the authors added, as this strategy can "optimize nutritional status and reduce postoperative complications."

A Crohn's disease exclusion diet, which involves partial enteral nutrition therapy, may be considered in mild or moderate cases, according to the update.

"Data on the use of enteral nutrition in the treatment of active ulcerative colitis are limited," the panelists wrote, although early data suggest it is safe and well tolerated, and can improve prealbumin levels.


Parenteral Nutrition

The update recommends short-term parenteral nutrition for patients with phlegmonous inflammation and/or an intra-abdominal abscess, as this can act as a bridge to surgical intervention.

Patients with prolonged ileus, short bowel syndrome, or high-output gastrointestinal fistula may also be candidates for parenteral nutrition, as well as those who have tried and failed both oral and enteral nutrition.

Lastly, the update encourages transition from long-term parenteral nutrition to oral intake and customized hydration management "whenever possible."


Monitoring and Multidisciplinary Care

The authors concluded by advising that all patients with complicated IBD be comanaged by a gastroenterologist and a registered dietitian, both of whom should remain watchful for signs of malnutrition.

Using serum protein as a surrogate marker of malnutrition is no longer recommended and there are different criteria that should be utilized to identify malnutrition. Routine iron and vitamin D testing are warranted, as well as B12 testing for patients with extensive ileal disease or a history of ileal surgery.
 
Thanks for the post.

The update suggests that exclusive enteral nutrition is a reasonable option to induce clinical remission and endoscopic response in Crohn's disease

An update to confirm what countless studies easily accessible from the BMJ made evident 40 years ago. The leisurely pace at which evidence from dietary interventions is put into clinical practice has caused a lot of harm.

If it wasn't for the work of Anthony Segal and the good people at Nestlé and Nutricia pushing this industry forward, we would still be nowhere. A lot more credit should be going to these people.

all patients with IBD follow a Mediterranean diet while minimizing salt, sugar, and ultraprocessed foods

This is not helpful advice, dietary recommendations need to be much more strictly defined.

1) No one agrees what a "Mediterranean" diet looks like.

2) The word "sugar" can refer to glucose, fructose, lactose, maltose, and a laundry list of "sugars" which can be obtained through hydrolysis with wildly different properties.

Vitamin D deficiency is more often associated with CD. There are emerging
data suggesting a novel role for vitamin D in immune homeostasis and improved ability to control chronic inflammation.

Good. This forum has been aware of this for a long time. Vitamin D activates autophagy necessary for bacterial clearance.
 
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Being dealing with crohns for 12 years for my kiddo and all of the data in the paper is what we have been told in pediatric Gi land for the past twelve years
So not new but just what has been the standard.
Not sure it has been the standard in adult Gi though .
 
I found only 2 actual patient studies regarding the Mediterranean diet and crohn's disease.

To say the evidence is weak is an understatement.

A Turkish study found no difference in CDAI score between crohn's disease patients adhering to a Mediterranean diet and those who did not.

A study from Pennsylvania found no evidence of a reduction in either CRP or a significant reduction in calprotectin with the meditterranean diet in crohn's disease patients.

More alarmingly, of the 28 with elevated CRP at the start of the study, only 1 out of 28 achieved a response on the mediterranean diet, 96% of participants still had significantly raised CRP at 6 weeks on the diet.

If anything, a mediterranean diet should be approached with caution.

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@kiny at least what we have been told was Mediterranean diet can’t be alone .
It is best to be used with medication.
Not as a monotherapy .
 
MD feels like a fine, well-balance diet choice for someone who has a healthy gut. For someone with Crohn's... all bets are off, especially when inflammation is raging. 🔥
 
I think that diet can help a a lot and is something advisable to do but unfortunately is not the final solution for the disease.
 

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