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<blockquote data-quote="copeland" data-source="post: 992671" data-attributes="member: 50463">Hi,I&#039;ve got a [wiki2=&quot;Perianal&quot;]perianal[/wiki2] [wiki2=&quot;Fistulas&quot;]fistula[/wiki2] (had it off and on for 14 years now).&nbsp; In the past, a quick course of antibiotics (Cipro and Flagyl) really helped to clear it up, sometimes for a relatively long time.However, this year it&#039;s come back and has been really hard to get rid of.&nbsp; I&#039;ve been on the antibiotics twice in the last 6 months and I&#039;ve only seen a little improvement while I&#039;m on them, and then as soon as the course is done the fistula is as active as ever within a week or so.&nbsp; I&#039;m also on 6MP and Cimzia right now, and nothing seems to be budging the fistula.&nbsp; My doctor wants to put me back on antibiotics, but I feel like they&#039;re just not working anymore.&nbsp; I also can&#039;t stand the taste of the Flagyl, so part of me just doesn&#039;t want to do that again, but I also think they&#039;ve lost their response.&nbsp; Anyone have any thoughts?Thanks,-Dan</blockquote>

[QUOTE="copeland, post: 992671, member: 50463"] Hi, I've got a [wiki2="Perianal"]perianal[/wiki2] [wiki2="Fistulas"]fistula[/wiki2] (had it off and on for 14 years now). In the past, a quick course of antibiotics (Cipro and Flagyl) really helped to clear it up, sometimes for a relatively long time. However, this year it's come back and has been really hard to get rid of. I've been on the antibiotics twice in the last 6 months and I've only seen a little improvement while I'm on them, and then as soon as the course is done the fistula is as active as ever within a week or so. I'm also on 6MP and Cimzia right now, and nothing seems to be budging the fistula. My doctor wants to put me back on antibiotics, but I feel like they're just not working anymore. I also can't stand the taste of the Flagyl, so part of me just doesn't want to do that again, but I also think they've lost their response. Anyone have any thoughts? Thanks, -Dan [/QUOTE]

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