Prednisone and Marijuana

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Sep 5, 2012
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Bremerton, WA
I use marijuana as a "home remedy" for some of my crohn's symptoms quite frequently. I'm also on 50mg of prednisone daily, as I'm dealing with a particularly bad flare. I've noticed that when I do smoke cannabis on high doses of prednisone, I have a very, very different high than when I don't have the roids in my body.

The high I get from the marijuana when I'm on prednisone often makes me very self critical, pessimistic and panicked. I find myself questioning everything and getting overly worried about little, insignificant things. I also tend to have troubles breathing and have even experienced something along the lines of a split personality when I smoke larger amounts...

I'm a pretty experienced smoker so I realize that many people experience paranoia when under the influence of marijuana, but this is a totally different feeling and it seems to only come when I'm on high doses of prednisone. Has anyone else noticed a negative interaction between the two in their own experience?
 
Its been year since I did both at the same time but that was around the time when I first started smoking it and I only noticed a happy type of high. Over the years in general I've become more and more paranoid when I smoke so I don't use it often at all. I've learned that if I just take one or two puffs at most then I'm good and don't need anymore than that otherwise the paranoia sets in for me. Maybe you could try one hit and just let that sit and see how well you do with that and take another as needed rather than an amount that you usually do. There are also strains that give you less of a high so maybe you could try those as well (indica).
 
Yeah, I've been trying out different strains and have decided to only take a few hits at a time because of the weird interaction. I've been smoking for a while now, so I've got a pretty good feel for the drug and the different strains and how it effects my body and my symptoms... I'm not particularly looking for a solution, I'm just curious as to whether or not anyone else has experienced a "bad trip" while taking high doses of prednisone...
 
I've never used cannabis while on prednisone....but I know prednisone messed with my mood. I've been using MM for a while and have built up a tolerance. 2-3 vape hits of hash a day keeps my UC at bay and I barely feel any psychoactive effects.

Maybe try lowering your intake of cannabis while on prednisone to avoid the unpleasant effects? It doesn't take a lot of weed to relax the gut :D I can see how prednisone and MM could lead to an unpleasant experience....stick with the indicas

Northern Lights #5 is perfect for me...:D
 
Yeah, I've found that taking two or three hits every once in a while still provides me with relief, while not interacting too bad with anything else I'm taking. Unfortunately, I don't have too much choice when it comes to strains, as I don't have a prescription. While I am from the Seattle area and could probably get one, I go to school in Idaho for most of the year, so I'm not really sure how that would work. Also, my parents are pretty against marijuana use, so I'm not really sure how to go about bringing it up with them, since they'd be the ones paying for it.
 
Also, my parents are pretty against marijuana use, so I'm not really sure how to go about bringing it up with them, since they'd be the ones paying for it.

My parents were not too keen on my use till they realized how much it helped. I showed them studies...I stopped all my other meds (that they were paying hundreds a month for)...and showed them my colonoscopy on meds vs only mmj. That made them into believers.

I know some people will have a negative view on cannabis regardless of what they are shown, but you gotta try. Show them some of the studies I posted in your other thread. Tell them how much it helps you. That's my only advice.
 
I find Mary Jane to be the most effective treatment out for symptoms, I'm still on pred, sometimes get paranoia but it goes away
 
The high I get from the marijuana when I'm on prednisone often makes me very self critical, pessimistic and panicked. I find myself questioning everything and getting overly worried about little, insignificant things.

It is the first time in my life I hear those words spoken by another cannabis user. I thought I was the only one in the world that sometimes felt this when under the effect. I must have asked a few dozen people and I was alone in this. Woohoo! :thumright:

I eventually realized there was a pattern of time when I felt like this and was able to attribute it to cannabis. I solved the problem by switching strain. I suspect the different amounts and ratios of cannabinoids in every strain will induce different effects.

I am starting my first dose of prednisone tomorrow morning. I will report back on whether this annoying thought pattern returns with it.
 
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