I posted this in the Parent's forum but thought the general forum might e a good place for this info too. If I shouldn't have posted twice, please let me know. Thanks.
1. Non-melanoma skin cancer may be the cancer to watch for in IBDers on thiopurines.
http://www.medscape.com/viewarticle/767304
2. New Therapies for IBD - a pretty technical discussion of new therapies for IBD organized by the treatment target. For example, suppressing the adaptive immune system vs. enhancing the innate immune system. I found this approach very helpful in understanding why a cocktail of meds may be most effective and why measures to improve immune function may sometimes make sense.
Much of the article was over my head but the beginning and end were pretty accessible/understandable to me. So you might just want to skip the stuff in between that contained sentences like:
"The process of leucocyte infiltration is governed by the expression of integrins and chemokine receptors (CCR) on leucocytes and adhesion molecules such as intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), and mucosal addressin cell adhesion molecule 1 (MAdCAM-1) on endothelial cells,[106 107] molecules that are upregulated in IBD.[108]"
http://www.medscape.com/viewarticle/763862
3. In "Are my patients taking their meds?" a Mayo clinic IBD doc says:
"A patient with Crohns disease has a 40% chance of recurrence (even if there has not been a flare for years) after the first year of stopping therapy."
4. Primary Sclerosing Cholangitis and UC:
UC does not appear to worsen the clinical course of PSC (liver)
http://www.medscape.com/viewarticle/761975
5. New med Golimumab looks very good in late stage clinical trials for treatment of moderate to severe UC
http://www.medscape.com/viewarticle/764224
6. So just what should UC patients expect when they are "in remission"? In depth discussion of how "remission" is currently defined and how it should/could be defined by doctors, patients and researchers.
http://www.medscape.com/viewarticle/746144
7. How to manage loss of response in CD patients by Dr. Lashner of Cleveland Clinic
http://www.medscape.com/viewarticle/760468
8. Is international travel safe? Is an IBDer more likely to get sick?
Probably not from regular illnesses but they may be more likely to flare according to this article.
http://www.medscape.com/viewarticle/762839
9. High-altitude travel including plane flights and trips to high altitude locations appear to increase likelihood of IBD flare
http://www.medscape.com/viewarticle/764258
1. Non-melanoma skin cancer may be the cancer to watch for in IBDers on thiopurines.
http://www.medscape.com/viewarticle/767304
2. New Therapies for IBD - a pretty technical discussion of new therapies for IBD organized by the treatment target. For example, suppressing the adaptive immune system vs. enhancing the innate immune system. I found this approach very helpful in understanding why a cocktail of meds may be most effective and why measures to improve immune function may sometimes make sense.
Much of the article was over my head but the beginning and end were pretty accessible/understandable to me. So you might just want to skip the stuff in between that contained sentences like:
"The process of leucocyte infiltration is governed by the expression of integrins and chemokine receptors (CCR) on leucocytes and adhesion molecules such as intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), and mucosal addressin cell adhesion molecule 1 (MAdCAM-1) on endothelial cells,[106 107] molecules that are upregulated in IBD.[108]"
http://www.medscape.com/viewarticle/763862
3. In "Are my patients taking their meds?" a Mayo clinic IBD doc says:
"A patient with Crohns disease has a 40% chance of recurrence (even if there has not been a flare for years) after the first year of stopping therapy."
4. Primary Sclerosing Cholangitis and UC:
UC does not appear to worsen the clinical course of PSC (liver)
http://www.medscape.com/viewarticle/761975
5. New med Golimumab looks very good in late stage clinical trials for treatment of moderate to severe UC
http://www.medscape.com/viewarticle/764224
6. So just what should UC patients expect when they are "in remission"? In depth discussion of how "remission" is currently defined and how it should/could be defined by doctors, patients and researchers.
http://www.medscape.com/viewarticle/746144
7. How to manage loss of response in CD patients by Dr. Lashner of Cleveland Clinic
http://www.medscape.com/viewarticle/760468
8. Is international travel safe? Is an IBDer more likely to get sick?
Probably not from regular illnesses but they may be more likely to flare according to this article.
http://www.medscape.com/viewarticle/762839
9. High-altitude travel including plane flights and trips to high altitude locations appear to increase likelihood of IBD flare
http://www.medscape.com/viewarticle/764258
