I was given steriods to taper off while the lialda built up in my system. Then I was given more prednisone while the 6mp built up in my system. Then I was given more prednisone to stop a flare and to get me through until I got my remicade infusions started. I always took my medicines along with prednisone(so sometimes I'd be on 6mp, lialda and prednisone)