My partner has Crohn's and gets a Remicade injection every 6 weeks. This has done wonders for his overall pain, but he still has an attack about once a month. When these happen, he takes 4-6 mgs of morphine sulfate for the pain. He reacts terribly to it - severe itchiness, sweating, runny nose, puffy face/eyes, difficulty breathing. He's clearly allergic to it. The discomfort keeps him awake for days, and after a couple of sleepless nights in this state he's a rambling, crazy mess. But his GP has told him there isn't much available for him outside the morphine family, at least not without going into a much stronger family of drugs. He was on hydromorph before with pretty much the same results; I'm sure anything morphine-based won't work. What other options does he have??