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Crohn's Disease Forum

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  1. Crohn2357

    (POLL) Were you exposed to cigarette/tobacco smoke before your Crohn’s diagnosis?

    The poll applies to all tobacco products; not just cigarettes.
  2. Crohn2357

    HLA-DQA1*05 Carriage Associated With Development of Anti-Drug Antibodies to Infliximab and Adalimumab in Patients With Crohn's Disease

    Observational Study HLA-DQA1*05 Carriage Associated With Development of Anti-Drug Antibodies to Infliximab and Adalimumab in Patients With Crohn's Disease Aleksejs Sazonovs et al. Gastroenterology.2020 Jan. Abstract Background & aims: Anti-tumor necrosis factor (anti-TNF) therapies are the most...
  3. Crohn2357

    Successful Treatment of Colorectal Anastomotic Stricture by Using Sphincterotomes

     Front Surg. 2014 Jun 20;1:22. doi: 10.3389/fsurg.2014.00022 Successful Treatment of Colorectal Anastomotic Stricture by Using Sphincterotomes Tzu-An Chen 1,*, Wei-Lun Hsu 2 PMCID: PMC4286977 PMID: 25593946 … Endoscopic incision for the treatment of anastomotic stenosis in the upper...
  4. Crohn2357

    Systemic lidocaine and mexiletine for the treatment of a patient with total ulcerative colitis

    LETTER Gut. 2005 Mar;54(3):441. doi: 10.1136/gut.2004.055525 Systemic lidocaine and mexiletine for the treatment of a patient with total ulcerative colitis Y Yokoyama 1, S Onishi 1 PMCID: PMC1774406 PMID: 15711001 In basic research, neural modulation in ulcerative colitis has been shown.1...
  5. Crohn2357

    What happened to David and many of the old members?

    The forum used to be very active. @David @hugh @D Bergy @mf15 and others come to my mind. Where are people? When they have issues with Crohn’s, do they post elsewhere? I’m interested in learning where people post to interact with, and learn from the other CD patients.
  6. Crohn2357

    Stelara every 4 weeks - how long does it take to notice the improvements?

    How long did it take for you to get into remission after your Stelara injection intervals were halved (from every 8 weeks to every 4 weeks)?
  7. Crohn2357

    Appendectomy and Proctitis

    In a prospective case series, 30 adult patients with ulcerative proctitis underwent an appendectomy, in the absence of history suggestive of previous appendicitis, in order to evaluate its potential therapeutic role [74]. After an appendectomy, the clinical activity index, calculated with the...
  8. Crohn2357

    Rectal Tacrolimus for Strictures Due to Crohn’s

    Simple water-based tacrolimus enemas for refractory proctitis Sasha R Fehily et al. JGH Open. 2019. Abstract Background and aims: Rectal ulcerative colitis (UC) and Crohn's disease (CD) often do not respond to conventional therapies. Oral and suppository tacrolimus are effective but often...
  9. Crohn2357

    GUT STERILIZATION FOR CROHN’S DISEASE (THEORETICAL CURE)

    This is an old article that I like. SUMMARY Achieving a substantial reduction in the bacterial flora of the gut is a theoretically attractive means of treating inflammatory bowel disease, particularly colonic disease. There are practical difficulties in obtaining a sustained reduction of the...
  10. Crohn2357

    Can You Eat Olives Without Any Issues? (POLL)

    Do you ever experience gut problems of any kind with olives, do you consider olives safe to eat? What kind of olives do you eat? How much and how often do you eat them? I have read about baked/roasted olives, I may try them to see if they are more tolerable with Crohn’s.
  11. Crohn2357

    “Sorriso Pharmaceuticals is creating the first orally-delivered anti-inflammatory drug for patients with IBD”

    https://www.utahbusiness.com/sorriso-pharmaceuticals-is-creating-the-first-orally-delivered-anti-inflammatory-drug-for-patients-with-ibd/
  12. Crohn2357

    Rapid Improvement and Remission in Patients With Refractory Ulcerative Colitis and Crohn’s Colitis After Direct Injection of Remestemcel-L by Colonosc

    https://finance.yahoo.com/news/rapid-improvement-remission-patients-refractory-231900721.html
  13. Crohn2357

    Can you eat dark chocolate and drink coffee without any problems?

    I can’t drink coffee, even a few sips give me abdominal pain, diarrhea etc.; but I can eat a little (10 grams?) dark chocolate (above 85% cocoa, the ones that don’t contain any dairy) every day. If I try to increase this amount, I get intestinal symptoms. I am curious if other Crohn’s patients...
  14. Crohn2357

    Food Additive Emulsifiers and Their Impact on Gut Microbiome, Permeability, and Inflammation: Mechanistic Insights in Inflammatory Bowel Disease

    Food Additive Emulsifiers and Their Impact on Gut Microbiome, Permeability, and Inflammation: Mechanistic Insights in Inflammatory Bowel Disease Aaron S Bancil, Alicia M Sandall, Megan Rossi, Benoit Chassaing, James O Lindsay, Kevin Whelan Journal of Crohn's and Colitis, Volume 15, Issue 6...
  15. Crohn2357

    Efficacy and safety of simultaneous treatment with two biologic medications in refractory Crohn's disease

    Aliment Pharmacol Ther 2020 Jun;51(11):1031-1038. doi: 10.1111/apt.15719.Epub 2020 Apr 24. Efficacy and safety of simultaneous treatment with two biologic medications in refractory Crohn's disease Edward Yang 1, Nicola Panaccione 2, Natalie Whitmire 1, Parambir S Dulai 1, Niels Vande Casteele 1...
  16. Crohn2357

    Mitochondrial impairment drives intestinal stem cell transition into dysfunctional Paneth cells predicting Crohn’s disease recurrence

    Mitochondrial impairment drives intestinal stem cell transition into dysfunctional Paneth cells predicting Crohn’s disease recurrence Sevana Khaloian1, Eva Rath1, Nassim Hammoudi2, Elisabeth Gleisinger1, Andreas Blutke3, Pieter Giesbertz4, Emanuel Berger1, Amira Metwaly1, Nadine Waldschmitt1...
  17. Crohn2357

    Incidence and prevalence of inflammatory bowel disease in UK primary care: a population-based cohort study

    Thomas Joshua Pasvol1, Laura Horsfall1, Stuart Bloom2, Anthony Walter Segal3, Caroline Sabin4,5, Nigel Field4,6, Greta Rait1,5 Received 27 December 2019 Revised 20 May 2020 Accepted 05 June 2020 Abstract Objectives We describe temporal trends in the recorded incidence of inflammatory bowel...
  18. Crohn2357

    Systematic review: gastrointestinal infection and incident inflammatory bowel disease

    Aliment Pharmacol Ther. 2020 Jun;51(12):1222-1232. doi: 10.1111/apt.15770. 2020 May 5. Systematic review: gastrointestinal infection and incident inflammatory bowel disease Jordan E Axelrad 1 , Ken H Cadwell 1 2 , Jean-Frederic Colombel 3 , Shailja C Shah 4 PMID: 32372471 PMCID...
  19. Crohn2357

    Serum Biomarkers Identify Patients Who Will Develop Inflammatory Bowel Diseases Up to 5 Years Before Diagnosis

    Serum Biomarkers Identify Patients Who Will Develop Inflammatory Bowel Diseases Up to 5 Years Before Diagnosis Joana Torres ∗ Francesca Petralia ∗ Takahiro Sato Mark S. Riddle § Jean-Frederic Colombel § on behalf ofthe Mount Sinai Road to Prevention Group Published: March 09, 2020 DOI...
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