i'm female, 64 yrs. old. started on 50 mg. 6mp in 2002 and went into complete remission. over time it's been reduced to 25 mg. which is low dose, but for me, the fatigue is bad; must nap daily and go to bed by 8:30. you'll need regular blood work. supposed to suppress the immune system making you available to colds, flu, etc. but from my experience, i'm very healthy and never get colds, flu. i bleed easily, even a nick on cuticle when getting nails done, causes bleeding and i've gotten little red marks all over my body. but, it's been a miracle drug and haven't had even a tiny flare since i started it. research the drug and learn everything you can about it. my hubby and i just work our lives around the fatigue. i take it at nite. tried taking during the day. for me, the fatigue is always there.