I've been taking 6MP for about 2 1/2 years, started at 75mg and raised to 100mg a year and a bit ago. I was normally around 147-154 pounds, but over the past few months (mainly due to feeling well) I've started eating more healthily and being more active (the latter only more recently though, I HATE exercise lol), and as a result I've lost around 14-17 pounds (it fluctuates) since being 147 pounds in July. I'm now around 130-133 pounds - not much for an adult male but I'm only 5'7".
Anyway, over the last few weeks I've had a rash develop on my upper body (neck, chest, back and arms). Not too much bother, just a bit itchy sometimes. I wondered if I was reacting to one of my meds, and I just had my 3 monthly blood test last week and was told for the first time that my liver bloods were a bit 'wonky'. Is this likely to be due to my recent weight loss - i.e. I'm now taking too much 6MP for my body weight? I've also noticed that I'm getting worse hangovers if I drink alcohol - I figured it was me just getting older haha but it may be that my liver function is a bit compromised now by this 100mg dose.
I've told my IBD nurse this today and I'm waiting for a response - I'm a little concerned though that my doctor is going to suggest a reduction back to 75mg. In some ways that would be GREAT - the first time since I developed this disease that my drug intake would be being DECREASED! But I'm at an awkward weight where I think my ideal/max dose would actually be something like 88mg - smack bang between 75 and 100, so 75mg might not be enough and I could run into problems. I was mildly symptomatic when I started my healthier lifestyle and I'm now symptom free - at first I wondered if it was just being healthier that had helped, but now I'm wondering if the weight loss has a resulted in a slight over-dose of 6MP which has totally knocked my colitis on the head but is now putting a bit of strain on my liver. In which case I don't want to reduce it!
I also don't want to be do anything hasty because I think I'm slowly going to gain weight through fitness. I did the healthier eating first without incorporating exercise (because I despise it) so I was just losing fat and not gaining muscle. For the past week and a half I've been working out daily and have noticed an increase in muscle, and I've gained a pound even though I've been eating the same amount as I was when I was losing a pound a week. If I keep going this way, replacing fat with muscle (which weighs more), then I could end up not too far off from the weight I started at (just with a better body shape) and 100mg would be the right dose again!
Apologies for the essay. I don't know if anyone will have any input (assuming you got to the end of my ramblings!), but I thought this might be interesting for others to read - something to watch out for if you're on a drug that's dosed based on your body-weight! It would be just my luck to get punished for finally getting fit haha.
Anyway, over the last few weeks I've had a rash develop on my upper body (neck, chest, back and arms). Not too much bother, just a bit itchy sometimes. I wondered if I was reacting to one of my meds, and I just had my 3 monthly blood test last week and was told for the first time that my liver bloods were a bit 'wonky'. Is this likely to be due to my recent weight loss - i.e. I'm now taking too much 6MP for my body weight? I've also noticed that I'm getting worse hangovers if I drink alcohol - I figured it was me just getting older haha but it may be that my liver function is a bit compromised now by this 100mg dose.
I've told my IBD nurse this today and I'm waiting for a response - I'm a little concerned though that my doctor is going to suggest a reduction back to 75mg. In some ways that would be GREAT - the first time since I developed this disease that my drug intake would be being DECREASED! But I'm at an awkward weight where I think my ideal/max dose would actually be something like 88mg - smack bang between 75 and 100, so 75mg might not be enough and I could run into problems. I was mildly symptomatic when I started my healthier lifestyle and I'm now symptom free - at first I wondered if it was just being healthier that had helped, but now I'm wondering if the weight loss has a resulted in a slight over-dose of 6MP which has totally knocked my colitis on the head but is now putting a bit of strain on my liver. In which case I don't want to reduce it!
I also don't want to be do anything hasty because I think I'm slowly going to gain weight through fitness. I did the healthier eating first without incorporating exercise (because I despise it) so I was just losing fat and not gaining muscle. For the past week and a half I've been working out daily and have noticed an increase in muscle, and I've gained a pound even though I've been eating the same amount as I was when I was losing a pound a week. If I keep going this way, replacing fat with muscle (which weighs more), then I could end up not too far off from the weight I started at (just with a better body shape) and 100mg would be the right dose again!
Apologies for the essay. I don't know if anyone will have any input (assuming you got to the end of my ramblings!), but I thought this might be interesting for others to read - something to watch out for if you're on a drug that's dosed based on your body-weight! It would be just my luck to get punished for finally getting fit haha.
