Eczema and psoriasis often flare with active Crohn’s disease, but the most common specific dermatological manifestation is erythema nodosum. Usually found at initial presentation, it settles with resolution of bowel inflammation rarely to recur.
Ocular inflammation usually presents as uveitis, episcleritis, or conjunctivitis. Crohn’s disease patients developing red eye, eye pain, and/or visual disturbance should receive emergency ophthalmic assessment. Persistently abnormal, particularly cholestatic liver function tests should prompt investigation including magnetic resonance cholangiography for primary sclerosing cholangitis.