Does Prednisone always work for you?

[whyclef]

Two weeks ago I had a four day stay at the Hospital for uncontrollable D and nausea. Ran more tests and found Crohns in colon plus same existing inflammation in Terminal Ileium. I'm now on 40mg Prednisone (Week 2) and Mesalamines. My symptoms of frequent D have not really improved other than increased appetite, accompanied by addition of joint pain, uveitis, and costochondritis. It seems like prednisone has made things worse... This happen to anyone else? Any thoughts or advise?

I am messaging the doctor at my Crohns clinic.

 

[Cross-stitch gal]

Hi. I guess I can say that pred usually seems to work on me. Even though, in the past I've been on it longer than the doctor really wanted me to be and also the side effects are pretty rough.

In your situation it sounds like it might not be a bad idea to contact your doctor like you said. Hopefully they'll have other ideas on how to help you better & sooner...

 

[whyclef]

Hi. I guess I can say that pred usually seems to work on me. Even though, in the past I've been on it longer than the doctor really wanted me to be and also the side effects are pretty rough.

In your situation it sounds like it might not be a bad idea to contact your doctor like you said. Hopefully they'll have other ideas on how to help you better & sooner...

Thank you for the feedback, waiting on hearing back from the Crohn's & Colitis clinic. I will post an update when I hear something.

 

[Cross-stitch gal]

Will be looking forward to your update! Hopefully you'll hear back from them soon...

 

[rygon]

Im not sure it made my crohns much better, but had some awesome dreams off it, got a better appetite, but I could see why it makes people suicdal, + when coming off it, t was pretty bad with me stomach. n the end they put me on remicade which helped loads

 

[sneezey]

I was in the hospital and really bad. Prednisone did nothing but improve my mood for about 10 minutes twice a day. Was told Remicade was more likely to be effective, so ended up on Cyclosporine which worked within 8 hours of starting.

Everyone is different, there is no one therapy that works every time for everyone.

 

[CrohnsChicago]

For me prednisone usually makes me feel almost entirely symptom free within two days of taking it. The most I have been on is 35mg. However, I have to deal with the numerous side effects that come along with this medication as most of us know well on this site.

You've got a double-whammy going on because of your flare AND uveitis. Definitely worth speaking to a doctor about. Let us know how it goes!

Hope you start to feel better soon!

 

[Jennifer]

Prednisone doesn't always work for everyone unfortunately. Sometimes it may simply have to do with being on too low of a dose in the beginning allowing things to get worse but honestly other times it depends on how aggressive the disease is. It's worked for me a couple of times in the past but not the last time I took it. Keep us posted.

 

[lizzy16]

The first time I was put on Prednisone was when I was first diagnosed and had been in bad pain for over a year - I started on 40mg combined with Asacol but I couldn't taper down to less than 20mg without getting really, really sick - I was on 20mg for at least 4 months and it didn't make me "well", it was just enough to keep the pain at bay while my docs decided what to do (I also moved from Birmingham to Manchester in this time so had to start again with new referrals, etc). It wasn't till I was hospitalised and given steroid infusions for a week, then followed with Pred and Azathioprine that I was able to feel better and achieve a remission. Now every time I flare and go on Pred it helps within 1-2 days and I feel normal again. Side effects are annoying, but it certainly does help me feel better.

 

[upsetmom]

My daughters been on prednisone twice the first time it worked within 2 days the second time it took about 10 days.

 

[Lisa]

In the past when I have been on pred it has worked for me fairly quickly - although I usually would be put on anything between 60-40 mg/day and tapered off from there.....never kept on it for long term though.....

 

[whyclef]

FOLLOWUP: Had an appointment on Friday at the Crohn's & Colitis Clinic in Dallas. My GI wants to start taper of Prednisone by 10mg per week and stop Apriso (thinks Apriso may have exacerbated symptoms). In return, he wants me to start steroid enemas for 2-3 weeks plus introduce Lialda. He also upped my dose of Lomotil to 8 pills a day as needed. Clarified that MRE showed Crohn's disease in the sigmoid colon, said if this does not work we do another colonoscopy with the possibility of disease in the TI.

 

[Cross-stitch gal]

Thanks for the update. Hopefully things will start working for you and you'll start feeling better soon. Take care. :hug:

 

[Dukeis]

FOLLOWUP: Had an appointment on Friday at the Crohn's & Colitis Clinic in Dallas. My GI wants to start taper of Prednisone by 10mg per week and stop Apriso (thinks Apriso may have exacerbated symptoms). In return, he wants me to start steroid enemas for 2-3 weeks plus introduce Lialda. He also upped my dose of Lomotil to 8 pills a day as needed. Clarified that MRE showed Crohn's disease in the sigmoid colon, said if this does not work we do another colonoscopy with the possibility of disease in the TI.

Apriso and Liada are both a form of Mesalamine. Wonder why the doctor would think the Apriso is exacerbating your symptoms and then put you on Lialda.

 

[greghensel]

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