wheat is one of the most likely contributors if not cause or causative factor of all autoimmune disease (through increased intestinal permeability).
"Based on our results, we concluded that gliadin activates zonulin signaling irrespective of the genetic expression of autoimmunity, leading to increased intestinal permeability to macromolecules."
Alessio Fasano, MD
Scandinavian Journal of Gastroenterology, 2006; 41: 408 Á/419
Gliadin, zonulin and gut permeability: Effects on celiac and non-celiac
interpreted by rob wolf
"Gluten attaches to the transpost molecule, CXCR3. This causes a release of zonulin which disolves the tight junction between intestinal epithelial cells (enterocytes) and THIS opens the door for autoimmunity and systemic inflammation."
That and being food for the bad bacteria, better to leave it right off the menu.
If you want to help your friend introduce him/her to paleo