My periods DEFINITELY made my symptoms worse. The only time I've achieved remission in 10 years was during my pregnancy, so afterwards I set out to find a birth control that mimicked the pregnancy hormone. I did find one that helped some, but it was very expensive. It was seasonique... which only gives you four periods a year. Never felt better! It may not have even been that particular BC that was so successful, maybe just not having such frequent cycles is what helped. Who knows... but my personal opinion is that hormones and stress have EVERYTHING to do with symptom flares!