I have just stopped Humira ( doc likes to call it a "humira holiday" as he wants me to take again) I found it causes festy lip sores like cold sores but they have been there since I started back on humira in february. I had them last year when I started Humira but didn't associate the 2 and went to dermotologist who checked for herpes and then took a biopsy - ouch - to tell me it's inflammation. I stopped the humira and the lip sores went away but the mouth ulcers flares to the poiint that even water hurts. I couldn't bear it so went back on the humira. BUT I am sick of these lip sores so am into my second week humira free with much mouth pain. I have also been on LDN since Jan but I have only just realised I was taking .3mg instead of 3mg( I use a syringe to measure and have been confused for 6 mths. Lets call it crohns brain fuzz.) I am slowly increasing LDN but really don't want to start back on Humira. The funny thing is that even on such a small dose of LDN my bm reduced massively. I know the ulcers are systemic and as all the specialists say "once you get the crohns under control you will fix the ulcers" - i see an oral pathologist - mouth wash dexmethisone 2 x a day am currently on reducing dose of prednisone. I have just found bonjella to provide some relief when I eat, but the ulcers are even on my tongue so I can't taste anything. ANY NEW SUGGESTIONS WELCOME:rosette1: