Kidney stones

[karlyg]

kidney stones

is it true that people with ibd are more prone to kidney stones? it would certainly make sense in my case as i had my first kidney stone about six weeks after my first flare came under control, and have had 4 kidney stones since then in the last 4 years. anyone know why this happens with us?

 

[old hat]

Yes

http://www.ccfa.org/info/about/complications/kidney

Kidney stones
These are probably the most commonly encountered kidney complications of IBD—particularly oxalate stones. Kidney stones are more common in Crohn's patients with disease of the small intestine than in the general population because of fat malabsorption. Fat binds to calcium, leaving oxalate (a type of salt) free to be absorbed and deposited in the kidney, where it can form into stones. The risk for developing kidney stones of this type is higher in people who have had a number of small bowel resections and are therefore more prone to dehydration. Their urine is more concentrated, a condition that is more likely to lead to stone formation. Symptoms may include sharp pain, nausea, vomiting, and blood in the urine. Kidney stone treatment calls for an increased fluid intake together with a low-oxalate diet (one that's rich in juices and vegetables).

 

[Kev]

Not sure of the connection between IBD & stones. I know from personal experience that one of the leading causes is dehydration... so anyone suffering from same due to repeated or extended periods of big 'D' would be more prone. I also heard that part of the problem has to do with calcium, and it's absorption. My doc's at the time (way back in the early 80's) told me to watch my calcium intake. But I gather that is no longer popular opinion, and in fact one should ensure that they get extra calcium.. but that you need another item (and my memory fails on what the right combo is) in order for your body to properly absorb/use calcium. I expect others will post with more definite and detailed info on the kidney stone issue, and how it correlates to calcium, IBD, and other essential elements, etc...

 

[Cara Fusinato]

Don't forget gallstones. Common -- gallstones, kidney stones both for us Crohnies.

We're stoners -- that's why certain states will issue "the card" for Crohn's.

Just kidding . . . but in truth, stone-making is popular with us. I have had gallstones (13 of them removed with the gallbladder AND about 5 bouts with kidney stones).

 

[old hat]

http://www.ncbi.nlm.nih.gov/entrez/...ve&db=PubMed&list_uids=12161938&dopt=Citation
Urinary patterns of patients with renal stones associated with chronic inflammatory bowel disease.Trinchieri A, Lizzano R, Castelnuovo C, Zanetti G, Pisani E.
Institute of Urology, IRCCS Ospedale Maggiore, Milano, Italy. [email protected]

OBJECTIVE: The aim of this study was to analyze the frequency of renal stone patients with chronic inflammatory bowel disease and their urinary patterns. METHODS: During a 20-year period, 1941 consecutive patients with renal stone disease underwent routine laboratory procedures including a fasting blood sample for chemistry profile and a 24-hour urine collection for analyses of electrolytes. Thorough histories including chronic inflammatory disease or ileal resection were obtained. Patients with inflammatory bowel disease together with a control group comprising 47 idiopathic renal calcium stone formers were submitted to a xylose absorption test for evaluation of intestinal absorption. RESULTS: We observed 10 patients with Crohn's disease, 12 with ulcerative colitis and one patient with ileal bypass for obesity. Six patients underwent ileal resection and 10 patients total colectomy. Urinary oxalate excretion was significantly higher and urinary citrate lower in stone patients with ileal disease (Ox 60 +/- 23, Cit 113 + 7-118 mg/day) than in idiopathic stone formers (Ox 28.2 +/- 11.5, Cit 381 +/- 205) and stone patients with ulcerative colitis (Ox 20.3 +/- 14.8, Cit 369 +/- 247). Urinary volume was significantly lower in patients with ulcerative colitis. A significant inverse correlation (-0.38, p < 0.01) between oxalate urinary excretion and blood xylose level was found 2 hours after ingestion of xylose. No significant reduction of xylose absorption was demonstrated in both normoxaluric and hyperoxaluric idiopathic stone patients. CONCLUSIONS: Crohn's disease and ulcerative colitis are characterized by recurrent inflammatory involvement of different intestinal segments involving distinctive urinary patterns. Malabosorption associated with ileal disease causes increased oxalate absorption by increasing oxalate solubility in the intestinal lumen and permeability of the colonic mucosa; a reduced citrate excretion is associated in relation to mild acidosis due to the loss of bicarbonate in the liquid stool. In ulcerative colitis, especially if an ileostomy is present, urine are scanty and concentrated, and urine pH falls, leading to uric acid or mixed stones. Mild hyperoxaluria of idiopathic renal stone formers is not related to subtle intestinal malabsorption.

 

[Isla]

Ugg I wished my kidney stones could be avoided. Mine get up to like 7 milimeters - the ER doctors always say to me "no hunny you don't pass kidney stones, YOU GIVE BIRTH TO THEM!!" They are amazed I can pass stones of that size so easily.

 

[Isla]

Ro?