I was diagnosed a few years ago with Crohn’s Colitis. I need some advice on choosing LDN or Humira.
I have been on the trial drug Vedolizumab for a year now to treat Crohn’s Colitis. It seemed to be working but in the last few months it doesn’t seem to be.
BM’s are 3-5 times daily. Sometimes very loose, sometimes solid, but almost always with blood and mucus. I’ve received 2 units’ of blood last week and Iron every 2 weeks for the past 2 months. My iron levels are having a hard time keeping up with the blood loss.
My last scope showed extensive inflammation in the sigmoid and descending colon. They didn’t proceed further to avoid the risk of damage. Prescribed 40mg of Prednisone and option of Humira or Remicade. A couple of the immunosuppressants were mentioned but I don’t want to go on those.
My goal is to reduce inflammation to prevent further damage, to prevent surgery. I am currently on Pentasa and just started Pred at 40mg last week.
Can I start taking LDN while tapering off Prednisone?
How soon will I notice a decline in inflammation 1) with LDN, 2) with Humira?
How soon will I start feeling better 1) with LDN, 2) with Humira?
Will there be obvious tell tale signs that the treatment is working 1) with LDN, 2) with Humira?
I really want to prevent further inflammation damage. If LDN can reduce the inflammation soon and rapidly, I am OK with not feeling super for a few months longer, if that means avoiding a biologic treatment in the long term. I just don’t want things to get any worse.
I understand that LDN may make people feel worse before they get better. Is this an overall judgement of their symptoms? I’m interested in knowing if there is an immediate effect on inflammation (increase or decrease)?
A possible scenario for me may be, to go on Humira to really to bring down the inflammation and promote healing. I can then decide later if necessary, to go off Humira and try LDN, if I’m feeling good vibes about LDN at that time.
The second option I have is to start taking LDN while continuing to taper off of the Prednisone and hope that the inflammation is brought under control. If I start feeling better I can stay the course. If I’m getting worse I can go for Humira. How long should I wait to make this decision though? One problem with me is that I really under evaluate how bad my condition is at a given time. I only notice it in hindsight. I can recall feeling just a little under the weather in the past, but now realize I was making those assumptions while not even being able to take out the garbage.
From what I read, Humira and LDN can’t be taken together, is this true? What about Vedolizumab?
Vedolizumab as far as I understand targets the white blood cells specific to the gut. Maybe LDN is OK to use with Vedolizumab.
I know that these will be repeat questions on this site. Sorry for that. I really don’t have enough time to read through everything by the time I have to make a decision.
Thanks.
I have been on the trial drug Vedolizumab for a year now to treat Crohn’s Colitis. It seemed to be working but in the last few months it doesn’t seem to be.
BM’s are 3-5 times daily. Sometimes very loose, sometimes solid, but almost always with blood and mucus. I’ve received 2 units’ of blood last week and Iron every 2 weeks for the past 2 months. My iron levels are having a hard time keeping up with the blood loss.
My last scope showed extensive inflammation in the sigmoid and descending colon. They didn’t proceed further to avoid the risk of damage. Prescribed 40mg of Prednisone and option of Humira or Remicade. A couple of the immunosuppressants were mentioned but I don’t want to go on those.
My goal is to reduce inflammation to prevent further damage, to prevent surgery. I am currently on Pentasa and just started Pred at 40mg last week.
Can I start taking LDN while tapering off Prednisone?
How soon will I notice a decline in inflammation 1) with LDN, 2) with Humira?
How soon will I start feeling better 1) with LDN, 2) with Humira?
Will there be obvious tell tale signs that the treatment is working 1) with LDN, 2) with Humira?
I really want to prevent further inflammation damage. If LDN can reduce the inflammation soon and rapidly, I am OK with not feeling super for a few months longer, if that means avoiding a biologic treatment in the long term. I just don’t want things to get any worse.
I understand that LDN may make people feel worse before they get better. Is this an overall judgement of their symptoms? I’m interested in knowing if there is an immediate effect on inflammation (increase or decrease)?
A possible scenario for me may be, to go on Humira to really to bring down the inflammation and promote healing. I can then decide later if necessary, to go off Humira and try LDN, if I’m feeling good vibes about LDN at that time.
The second option I have is to start taking LDN while continuing to taper off of the Prednisone and hope that the inflammation is brought under control. If I start feeling better I can stay the course. If I’m getting worse I can go for Humira. How long should I wait to make this decision though? One problem with me is that I really under evaluate how bad my condition is at a given time. I only notice it in hindsight. I can recall feeling just a little under the weather in the past, but now realize I was making those assumptions while not even being able to take out the garbage.
From what I read, Humira and LDN can’t be taken together, is this true? What about Vedolizumab?
Vedolizumab as far as I understand targets the white blood cells specific to the gut. Maybe LDN is OK to use with Vedolizumab.
I know that these will be repeat questions on this site. Sorry for that. I really don’t have enough time to read through everything by the time I have to make a decision.
Thanks.
