Modern wheat is a "perfect, chronic poison"

[David]

Modern wheat is a "perfect, chronic poison," according to Dr. William Davis, a cardiologist who has published a book all about the world's most popular grain.

Davis said that the wheat we eat these days isn't the wheat your grandma had: "It's an 18-inch tall plant created by genetic research in the '60s and '70s," he said on "CBS This Morning." "This thing has many new features nobody told you about, such as there's a new protein in this thing called gliadin. It's not gluten. I'm not addressing people with gluten sensitivities and celiac disease. I'm talking about everybody else because everybody else is susceptible to the gliadin protein that is an opiate. This thing binds into the opiate receptors in your brain and in most people stimulates appetite, such that we consume 440 more calories per day, 365 days per year."

*snip*

Source

Does anyone know much about gliadin? I'll be researching it when I have a chance, but I haven't heard of this before.

 

[David]

That didn't take long:

Antibodies against gliadin of the IgA class were assessed with an enzyme-linked immunosorbent assay technique in children with celiac disease, healthy blood donors, and adult patients with active Crohn's disease or ulcerative colitis. Significantly higher antibody values were found in celiac children during gluten challenge and during the first 3 months on a gluten-free diet, compared with the findings in the healthy blood donors. The patients with active Crohn's disease had significantly higher levels of IgA antibodies to gliadin than the controls did. Although the highest values were found in patients with celiac disease on a gluten-containing diet, the difference between the means of these two groups was not statistically significant. No correlation was found between disease activity in ulcerative colitis and antibody values. The present results support the view that high levels of IgA-class antibodies against gliadin are indicative of small intestinal disease, especially celiac disease. The variability of the levels of antibodies found among the patients suggests that not only the amount of gluten in the diet but also other factors are important.

Source

 

[kiny]

was waiting to post this, it's from Metabolome and inflammasome in IBD. RADU M. NANAU, and MANUELA G. NEUMAN

Autoantibodies. The presence of several anticarbohydrate
antibodies [antibodies against mannan and
mannan residues, antichitobioside carbohydrate immunoglobulin
A (IgA) antibodies (ACCA), antilaminaribioside
carbohydrate IgG antibodies (ALCA),
antimannobioside carbohydrate IgG antibodies
(AMCA), and antichitin IgA and antilaminarin IgA],
anti-Saccharomyces cerevisiae IgA and IgG antibodies
(gASCA), perinuclear antineutrophil cytoplasmic
IgG antibodies (pANCA), antinuclear associated
antieutrophil IgG antibodies (atypical pANCA), serum
IgA and IgG autoantibodies to intestinal goblet
cells (GABs), serum IgG and a combination of IgG
and IgA autoantibodies to exocrine pancreas (PAB),
and IgA antibodies against porin protein C of Escherichia
coli (anti-OmpC) were assessed as potential serological
diagnostic markers in various cohorts of IBD
patients.

I think it would be nice to get alist of immunoglobulin reactions, would be nice if someone has the time.

 

[kiny]

these are my tests as a crohn's disease person for gliadin, all negative

Immunology

TranslutaminaseIGA < 0.1 U/ML
Meaning: LR < 1: lowered disease chance
LR > 1: higher disease chance
LR < 0.1: disease negative
LR > 10: disease positive

Allergy Tests
Anti-gliadine IgA 0.60 U/mL
Anti-gliadine IgG <0.40 U/mL

 

[kiny]

Made list through looking at 2 studies, these are not my results, study ones.

the. ++ means associated with crohn versus control -- means it's not.

ALCA ++crohn
ACCA ++crohn
pANCA --crohn (++UC)
anti-OmpC (E coli) ++crohn (--UC)
ASCA ++crohn
AMCA ++crohn
antichitin ++crohn
antilaminarin ++crohn
calprotectin ++crohn ++UC
GAB --crohn ++UC
PAB ++crohn
Anti-MAP ++crohn

ACCA = antichitobioside carbohydrate antibodies
ALCA = antilaminaribioside carbohydrate antibodies
ASCA = anti-Saccharomyces cerevisiae antibodies
AMCA = antimannobioside carbohydrate antibodies
anti-OmpC = antibodies against porin protein C of Escherichia coli
GAB = autoantibodies to intestinal goblet cells
MAP = M. paratuberculosis antibodies