Hello,
I took entocort for a while last year, when I started it, I was still taking pred, I was tapering up the dose of entocort while tapering down the dose of pred because I was having a lot of problems tapering pred on its own. I was told that it can take entocort 2-4 weeks to get to a level where you feel better. This is partly because it is not a systemic steroid like pred is, so it only targets surface inflammation in the bowel and not inflammation every where in the body. One of the reasons doctors favour it for long term or recurrent use instead of pred is that it has far fewer side effects, and although large doses can cause some calcium deficiency, it is not usually on the scale that pred would cause. Have you had your calcium levels checked recently? What about other vitamins and minerals? I get brittle nails whenever I feel run down and when I have severe aneamia (and I've always got too much calcium not too little), so this could be a possibility for you. Also, deficiencies are common in crohns because of the difficulty absorbing foods so any deficiency you do have won't always be a result of medications.