Need Some Help With LDN

[DaGreek]

I plan on having one of my doctors prescribe this for me, as I have Crohns, unfortunately the only kind I can get is Revia tablets in 50mg. I Live in Michigan and called a couple placed and Walgreens said they could crush the pills up and get it as close to 4.5mg as possible or something but they couldnt tell me more without me having a prescription. Would taking half a 50mg be bad? Or maybe even a 1/4th? If I cant get anyone to compound it for me? Thanks in advance

P.S. anyone heard of methylnaltrexone? Heard it may be better because it doesnt cross the blood brain barrier? Whatever that means :/

 

[Guest9283]

Yes it would be a very bad idea, especially considering we don't exactly know how the mechanism works with the immune system. No studies on that dosage and someone with an autoimmune disease. There are pharmacies that do compounding once you get a prescription. If not I would have the pharmacy crush em ( the 50's)

 

[DaGreek]

Alright, Thanks for the prompt response. I have one more question....I am going to start MM soon and want to take it with LDN.....will this be ok?

 

[ctrl z]

Everything I've read has stated it will be fine to use cannabis with LDN. I can dig around for some studies if you'd like to see for yourself.

Edit: Actually... here you go. It's about Naltrexone 25mg but if it is safe at that amount then certainly LDN is safe with cannabis.

Naltrexone does not attenuate the effects of intravenous Δ9-tetrahydrocannabinol in healthy humans.​

 

[DaGreek]

Thanks very much, one more question for you guys. Do you take 4.5mg once daily? I want to know what is recommended because im sure my doctor wont have a clue

 

[ctrl z]

Yes. From everything I've heard or read, you are supposed to take it once daily. There are links to LDN studies here. You should print them out and take them to your doctor.

 

[Kev]

4.5 mg, once a day. I've found that taking it right before going to sleep... sleep, Vs awake in bed, is best for me. I've never had any side effects other than vivid dreams that sadly have since stopped. I have heard that taking it at other times (annecdotally) may cause some to feel 'wired'... and some report taking it at bedtime (whether that is just before going to sleep or when they crawl into bed wasn't specified) cause disruptions to their sleep... sort of like wired at night. Like I said, nothing along those lines has ever happened to me.