Has anyone ever experienced hair loss when tapering off of prednisone? I have been on and off prednisone for the past two years, and it seems like every time I taper I start losing my hair! I now have about 1/3 of the hair I originallly had, and it's very frustrating! If I were a guy I would just shave my head, but since I'm a girl, it's pretty embarrassing! Thankfully I started out with a lot of hair. please help! I also had kidney failure about a year ago. I've talked to my doctors, but they don't ever really seem to answer why i'm losing my hair. Oh and thankfully, this is the LAST time I will be tapering off prednisone for a while at least! YEs!!!