Thanks for posting. The research was held in Tunisia, a north african country where crohns has dramatically increased in the last decade, according to my GI who is in contact with other GI's in north Africa. In Tunis, the capital, people live the western lifestyle grocery shopping and eat processed food in mass, slowly reducing the amount of fresh fruits, vegetables and natural home cook meals intakes, a new recent phenomenon, which I strongly belive is responsible for this sudden increase in IBD. Most 50 yld and up are also overweight and thus diabetes, extremly common.
Conclusions of the research is that thiopurine is overall safe. however the fallow up is only 6 years.
I was on them for 6 years and unfortunately i didnt have proper monitoring with blood check up. I prolly overdosed under that treatment without being aware of it. My new GI did proper monitoring on my second attemp with thiopurine and results came back really abnormal on the same dosage I was for several years before... We had to decrease the dose, a lot... For most of us wo do not react negatively in the first years of consuming these drugs, only long term research and experience will tell if these drugs are toxic or not...
