What can interfere with Faecal Calprotectin test results?

[jac521]

I have not had the Faecal Calprotectin test and was wondering what medications, etc. might interfere with the test results?

Thanks. Jac

 

[David]

In adult patients, FC showed 64% sensitivity and 80% specificity with 70% positive and 74% negative predictive values for organic causes. False-positive results (8 of 40 cases) were associated with the use of aspirin (3 cases) or nonsteroidal antiinflammatory drugs (1 case) and with the presence of concomitant liver cirrhosis (3 cases). False-negative results mainly included patients suffering from celiac disease (5 cases). Patients with IBD (9 cases) were identified with 100% sensitivity and 95% specificity. In pediatric patients, sensitivity was 70%, specificity was 93%, and positive and negative predictive values were 96% and 56%. False-negative results (11 of 35 cases) were associated mainly with celiac disease (6 cases) or intestinal giardiasis (2 cases).

Source

It really is a great test though.

 

[Lustforlife]

I thought I read somewhere but maybe I was wrong...can gastritis lead to elevated FC results?

 

[Johnnysmom]

Our GI said a stomach/intestinal virus can also affect the results.

 

[lubnaexperts]

can nexium or clarinase or zithromax affect the results of calprotectin

 

[SarahD]

There is some research showing that protpn pump inibitors's, like Nexium, can significantly elevate fecal calprotectin levels.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520167/

 

[lubnaexperts]

thank u sarah for that I hope that his calprotectin will be reduced again as I dont want to give him humira