I haven't had a huge amount of success with any pain relief, excluding huge doses of IV morphine at hospital.
I have in the past tried paracetamol, Nurofen plus (12.5 mg codeine + 200 mg ibuprofen). Neither of these had any effect at all.
My GP then prescribed me with codeine phosphate 30mg tablets (no other additives), This was 2 tablets as needed.. I didn't get any relief from, 2, 3, or 4 of these tablets. It was when I took 6 tablets (180mg) that I found some pain relief. It is worth noting that I certainly didn't experience any of the other "relaxing" opioid effects prior to the 180mg dose.
I discussed this with my Gastro, who decided it would be appropriate to prescribe me Endone 5mg (Oxycodone Hydrochloride) So far, I have had no relief when taking either one or two of these tablets (5-10mg). I'm certainly not keen to push the dose any further without my doctors' advice as I am acutely aware of the addictive properties of these medications through my line of work.
I have never had opioid based medications prior to what I have mentioned above. So I seem to just have an unusually high tolerance to them, or my body just can't metabolise/absorb opioids as well as other people. Which leaves me in a bit of a pickle of having to ask for huge quantities, and not look like junkie!
I don't require pain relief every day either. Only occasionally if the pain has been quite strong, for most of the day, and it just becomes too tiring to put up with anymore. I'm basically always in some sort of pain, but some days is just worse than others.
- And that my friend, is my experience with opioids.