Why does Humira have to be refrigerated?

[Chad K]

Why does Humira have to be refrigerated?

I know this is probably a question for those that make it. Just curious if anyone here knows the answer. After coming home from work (about a 10 hour day) I found that my refrigerator was open about an inch. It was a hot day. Some of the stuff in there was warm, and I am worried that the Humira may have went bad. Of course, I immediately closed the fridge door and got the medication cold again, but now I am very worried. Has anyone had this happen to them?

Any input would be greatly appreciated!

 

[Orchid]

It should still be usable for the next two or so weeks, as long as your next injection is before then it should be fine. It should however be considered to be on borrowed time because it possibly got above temperatures conductive to starting the process of the antibodies breaking down.

 

[nogutsnoglory]

You can call Abbvie to inquire as to whether it's okay but most likely yes. I had a power outage and they said it was ok because they had studies indicating it could sustain for a few hours in temperatures a little lower. The best thing is to explain it to them and if they feel it's not good they may ship a new one

 

[theOcean]

As long as your Humira wasn't laying in the sun it should be fine. It lasts up to two weeks unrefrigerated before the efficacy becomes questionable.

 

[nogutsnoglory]

Theocean I think after 24 hours below 50 degrees it's questionable. Do you have a source?

 

[theOcean]

Progressive, who supplies my Humira. I've asked them about it before after forgetting my pen out.

 

[nogutsnoglory]

Was it a nurse or just a rep? I'd be very iffy on whether the medication is active after such a period of time.

 

[theOcean]

A nurse, I think. I get called every month to answer questions about my Humira use and if I have any concerns or questions to ask them about the medication. I was told it's made to last much longer now. I know there's been another member on the forum with Progressive too who's said the same.

 

[nogutsnoglory]

That would be fantastic. I was on Humira a few years ago. Maybe they added a preservative.

 

[theOcean]

It seems like they may have! I can always ask and confirm next time I hear from them, which should be soon.

 

[Chad K]

Thank you everyone for all your feedback, this makes me feel so much better! I may call Humira as soon as I get a chance after work. If I receive any additional information I will let you all know.

Thanks so much!

 

[Orchid]

The catch it's good for two weeks unrefrigerated but once they've been exposed to temps high enough to start the breakdown as far as I understand it, it can't be stopped.

 

[theOcean]

Belated, but wanted to resurrect this thread since I went to my provider's website to confirm: