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Can you share which centres are doing research on VEO CROHN'S disease? And any idea by when they will come back with their findings?

I would like to use an analogy - diabetes in children vs diabetes in adults. And with Crohn's, no one knows the root cause. It is highly likely that the causes are different. Having said that, the treatments have got lot of commonalities.

@Scipio actually I found some research https://medicalxpress.com/news/2021-11-scientists-key-trigger-crohn-disease.html Perhaps there is a cause of Crohn's which causes the gut microbiome imbalance.

FMT transplant trial on paediatric IBD patients was done and results published. https://classic.clinicaltrials.gov/ct2/show/NCT02108821 The results were not conclusive for Crohn's.

Hi @Scipio sometimes I think the answer to it may not be so important whether Crohn's is causing the imbalance or imbalance causing Crohn's. If a way is found to fix the gut microbiome imbalances it will be a huge achievement in terms of treatment and help sufferers of Crohn's. Current...

@kiny - Thank you for posting this. This is a long read and perhaps require a few days and I may have to read it multiple times. A quick glance read suggests that candida tropicalis fungus is present in significantly higher quantity in patients with Crohn's than non-Crohn's. Perhaps the...

It is possible that they may be overselling it. As I have said, this by itself has to lead to a successful clinical trials of newer medications. I think the reason it took so long was because they actually monitored healthy relatives along with the people who had Crohn's or went on to develop...

https://www.newswire.ca/news-releases/canadian-medical-research-breakthrough-gut-bacteria-combination-shows-risk-for-crohn-s-disease-849544080.html I watched the youtube video and they claim that this is ground breaking. Let's hope it can result in newer treatments which are safer with...

Nanomedicine for treating inflammatory bowel disease Anti-inflammatory nanoparticles mimic glycocalyx https://www.sciencedaily.com/releases/2023/07/230717115853.htm I hope these researchers can carry out clinical trials soon.

@Scipio , @my little penguin , @Maya142 and other moderators & anyone who would like to share their thoughts. There are quite a number of studies all stating different genes as causing Crohn's disease. https://www.sciencedaily.com/releases/2018/09/180918110948.htm - RNF5 gene...

@sjiadad - I am so sorry that your son is going through this terrible ordeal. I hope that your son's doctors find a treatment soon which will work.

another interesting study https://www.news-medical.net/news/20221005/Study-may-have-solved-a-mystery-surrounding-Crohne28099s-disease.aspx

I came across this link today only. Researchers discover the cause of severe inflammatory bowel disease (IBD) https://www.thebrighterside.news/post/researchers-discover-the-cause-of-severe-inflammatory-bowel-disease-ibd?utm_source=flipboard&utm_content=other I hope new pathways for...

@Scipio thanks for sharing. A quick browse through the link and it seems that a lot more research is required for this and the challenge is who will fund it and take it step by step to some sort of treatment.

https://www.news-medical.net/news/20230517/Using-synthetic-peptides-for-inflammatory-disease-diagnosis.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=clinical_and_lab_diagnostics_newsletter_30_may_2023

Hi Bufford - all I can say is stay strong and healthy. There is no panacea when families go through a tense period. But stay hopeful and if possible stay assertive.

Thanks for your response. Very informative. Because Crohn's is a complex disease, the treatment may also be complex and this line of treatment should definitely be explored. I hope some pharmaceutical company takes this challenge. It will be a real tragedy if no company takes it up.

https://www.sciencedaily.com/releases/2023/04/230404114152.htm

@Scipio - you have perhaps more knowledge than I have. What do you think is the potential of this to be successful.

https://www.sciencedaily.com/releases/2023/02/230228113739.htm I don't know if they are going to carry out clinical trials but it will be really interesting if clinical trials are successful.