Drug advice
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theOcean
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It shouldn't, but if you were trying to conceive it may have an effect on the child. Maybe consult with the Trying To Conceive section of the forum? If that's not the goal I would think your partner should be fine, though.
EDIT: Searched and saw mothers reporting that they even took 6mp throughout pregnancy, so I would think it's definitely fine.
EDIT: Searched and saw mothers reporting that they even took 6mp throughout pregnancy, so I would think it's definitely fine.
PsychoJane
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6-MP was one of the drug my GI was really not worrying about during pregnancy at the least when it is the mother that takes it. I am looking in papers to find information regarding the father(taking the 6-MP) and the risks that it carries.
It seems that the researches that were done at the beginning of last decade were pointing towards a possibility for an increased risks of congenital abnomalies. Though, another study have been published, Hoeltzenbein et al. (2012) that came to the conclusion that the risks were not really increased and that "[a]lthough data are still limited, [they] see no need for termination of a pregnancy or invasive diagnostics only because of paternal treatment with AZA or 6-MP."
An article of journal of gastroenterology was suggesting the following regarding these drugs (Burton et al.(2000)) :
I am the precautionary type of gal but if the pregnancy is desired, I would rather try to find a good team of ob-gyn just to make sure you have the optimal follow-up with a high-resolution fetal ultrasonography to allow you to screen for birth defect if ever that were to happen.
Burton I Korelitz, Ramona O Rajapakse, Jusuf Zlatanic, Peter J Baiocco, Gilbert W Gleim, 6MP for fathers with IBD at the time of conception: the value of a large clinical experience over unrelated controls, The American Journal of Gastroenterology, Volume 95, Issue 9, September 2000, Pages 2386-2387
Maria Hoeltzenbein, Corinna Weber-Schoendorfer, Cornelia Borisch, Arthur Allignol, Reinhard Meister, Christof Schaefer, Pregnancy outcome after paternal exposure to azathioprine/6-mercaptopurine, Reproductive Toxicology, Volume 34, Issue 3, November 2012, Pages 364-369)
It seems that the researches that were done at the beginning of last decade were pointing towards a possibility for an increased risks of congenital abnomalies. Though, another study have been published, Hoeltzenbein et al. (2012) that came to the conclusion that the risks were not really increased and that "[a]lthough data are still limited, [they] see no need for termination of a pregnancy or invasive diagnostics only because of paternal treatment with AZA or 6-MP."
An article of journal of gastroenterology was suggesting the following regarding these drugs (Burton et al.(2000)) :
.”
I am the precautionary type of gal but if the pregnancy is desired, I would rather try to find a good team of ob-gyn just to make sure you have the optimal follow-up with a high-resolution fetal ultrasonography to allow you to screen for birth defect if ever that were to happen.
Burton I Korelitz, Ramona O Rajapakse, Jusuf Zlatanic, Peter J Baiocco, Gilbert W Gleim, 6MP for fathers with IBD at the time of conception: the value of a large clinical experience over unrelated controls, The American Journal of Gastroenterology, Volume 95, Issue 9, September 2000, Pages 2386-2387
Maria Hoeltzenbein, Corinna Weber-Schoendorfer, Cornelia Borisch, Arthur Allignol, Reinhard Meister, Christof Schaefer, Pregnancy outcome after paternal exposure to azathioprine/6-mercaptopurine, Reproductive Toxicology, Volume 34, Issue 3, November 2012, Pages 364-369)
