Is this biopsy enough for an official Crohns diagnosis?

[friendlylili]

Just got the biopsy results back. Colonscopy showed aphtous ulcers (didnt say with inflammation) in ileum. And a continous inflammation in colon and rectum along with erosions.

These are the biospy results.


1- Ileal mucosa within normal limits. (Ileum biopsy)

2- Minimally inflamed colonic mucosa with scattered, non-necrotizing epithelioid granulomas. (Ascending colon and cecum biopsy)

3- Minimally active follicular colitis. (Left and tranverse colon biopsy)

4- Moderately active colitis with a few questionable microgranulomas. (Sigmoid and rectum biopsies)

Notes:

• No dysplasia seen.
• Crohn disease should be excluded in first place.

Is this a death sentence? Ive no idea what to expect im new to all this. I will be going to a gastroenterologist next week.

Important (ig): No one in my family has Crohns. Not on my moms side or dads side. But on my dads side, we have Behcets disease. Which also causes inflammation.
But not Crohns. Ive no idea where this came from.

symptoms: loose BMs tho sometimes good. (1 BM a day)

Gas.

Sometimes mild abdominal pain.

Epescleritis (i think, not diagnosed)

I had blood in toilet water once (whichs why i got the colonscopy in the first place), its good now, stopped happening.

Thats probably it.

Im mostly normal. Like 95% of the time i pretty much am in a decent shape.

No fatigue.

I actually gained 5kgs in last month and a half.

Blood work good. No anemia.

Calprotectin: 442.

CT will be done in feb.
Appointment to gastro this month on the 28th.

Ive no idea what to expect. I sure hope to God its not Crohns. But if it is, what kind of treatmrnt should i ask the gastro to put me on guys. I heard biologics have cancer risk.

 

[my little penguin]

First breathe
Crohns is not a death sentence
Under treated crohns can cause cancer
Biologics are fine
My adult college age “child” was dx with crohns at age 7
Biologics at age 8
No issues living the normal life and in college now .
That said bechets can be intestinal bechets which mimics crohns /colitis in some folks so be sure to visit a rheumatologist as well and let the Gi know you have a family history of bechets .

For the intestinal version of bechets or for Crohn’s disease both are treated with the same meds
Immunosuppressants (methotrexate or 6-mp/imuran )
If those don’t work they tend to move onto biologics -remicade /humira /stelara /entvyio

Good luck at the Gi
They may order imaging
MRE (mri with entography ) and capsule endoscopy (pill cam)
These tests give full picture
Hugs

 

[friendlylili]

First breathe
Crohns is not a death sentence
Under treated crohns can cause cancer
Biologics are fine
My adult college age “child” was dx with crohns at age 7
Biologics at age 8
No issues living the normal life and in college now .
That said bechets can be intestinal bechets which mimics crohns /colitis in some folks so be sure to visit a rheumatologist as well and let the Gi know you have a family history of bechets .

For the intestinal version of bechets or for Crohn’s disease both are treated with the same meds
Immunosuppressants (methotrexate or 6-mp/imuran )
If those don’t work they tend to move onto biologics -remicade /humira /stelara /entvyio

Good luck at the Gi
They may order imaging
MRE (mri with entography ) and capsule endoscopy (pill cam)
These tests give full picture
Hugs

thanks for the answer bro. Can the biopsy indicate anything other than Crohns? Or are granulomas exclusive to crohns disease.

I actually feel like it might be UC. Cus of the continous inflammation and the involvment in Rectum (Crohns inflammation is often patchy and spares rectum). Also no inflmattion in ileum apart from few apthoids (which might be cause by something else completely.).

But i heard granulomas only occur in Crohns and not UC. But it doesnt sound like Crohns to me. Especially since the inflammation is continous and invlolves the rectum too.

Ive sent the biopsy to three Docs. All three said: "you have a mild inflammation that doesnt necesarrily mean Crohns, but docs should rule out Crohns too".

How come they didnt say its Crohns as granulomas are present? Any idea?

Thanks and may God bless your sons heart and give him health and wealth.