Need Explanation of How LDN Works For Dummies!

[jac521]

I am quite new to the forum and this is the first I have heard of LDN being used for Crohns. I have searched through the articles and studies on LDN, but I just can't seem to understand how LDN works for Crohns.

Could someone explain to me in simple language about LDN?

Thanks!!!

 

[ctrl z]

From LDNscience.org

Since LDN blocks the OGF receptors only for a few hours before it is naturally excreted, what results is a rebound effect; in which both the production and utilization of OGF is greatly increased. Once the LDN has been metabolized, the elevated endorphins produced as a result of the rebound effect can now interact with the more-sensitive and more-plentiful receptors and assist in regulating cell growth and immunity.

The endorphins that are produced help heal the body.

I think that's as simple as it gets! I hope that helped. I don't think it is even completely understood how it works in Crohn's by the scientists that are studying it. I could be wrong. If that wasn't a good enough explanation then hopefully someone else can give you a better one :smile:

 

[Jmrogers4]

^^^ Yeah that. Jack's GI basically told us we're not sure how it works.

 

[jac521]

Thanks cntrl z - Do you know if LDN helps extra intestinal manifestations of Crohns as well as Crohns related arthritis?

Thanks.
Jac

 

[ctrl z]

I'm not sure. I don't suffer from arthritis or any other extraintestinal manifestations but I have read about people with rheumatoid arthritis getting relief from LDN over time. The thing with LDN is that it takes a long time to work for Crohn's so if you have anything major going on, you should get it under control before you start LDN.

 

[Kev]

No can do. I could guess, but why? Think about this. Consider all the technology you used to get here, post this thread, read the replies. Do you know exactly how all of that worked? Some things one doesn't question. Or, at least, if they work, why question it?

 

[ctrl z]

Because knowledge is power?

 

[Jmrogers4]

Thanks Ctrl Z, I'm off to bed now with School house Rocks running through my head

 

[ctrl z]

Haha! :biggrin:

 

[mnsun]

For me, I noticed my joint pain, in the SI joint, increasing as the season shifted into Fall/Winter. I started LDN a few months later, hoping this would help; however, it didn't help me much in that department. Not until I started taking 5000iu D3, daily, did I see sustained improvement of joint pain.

For me, my joint pain is DEFINITELY tied directly to D3 levels, though I've never been tested. I do have paper work to get the labs done; I just don't know how much it is, but I'll spring for it eventually. I still take 5000iu D3 daily, but every couple months I may have a couple hours of SI discomfort, as opposed to the 2-5 day streaks I was having. So, perhaps, I may need to take more every so often--it is pretty hard to overdo D3. Not once since supplementing daily throughout the Fall/Winter months this year has my pain been bothersome for more than a couple hours--I mean, like one time in the past 4 months. Huge improvement compared to last year.

I do know a Lymes patient who accredits LDN with stopping her unbearable joint pains that left her bedridden for days on end.