- Joined
- Jun 18, 2011
- Messages
- 35
possible useful information about crohns/colitis.
My researching, as limited as it is, has landed me upon a few things that i feel i should share with those of you who want more than a serious-side-effect-pharmaceutical suppression of the disease, but an understanding of it and how to perhaps naturally combat it.
http://en.wikipedia.org/wiki/Helminthic_therapy
i found this very interesting.Incidence of autoimmune diseases and parasitic infestation
"While it is recognized that there is probably a genetic disposition in certain individuals for the development of autoimmune diseases, the rate of increase in incidence of autoimmune diseases cannot be explained by genetics alone. There is evidence that one of the primary reasons for the increase in autoimmune diseases in the industrialized nations is the significant change in environmental factors over the last century. Environmental factors include exposure to certain artificial chemicals from industrial processes, medicines, farming and food preparation. It is posited that the absence of exposure to certain parasites, bacteria and viruses is playing a significant role in the development of autoimmune diseases in the more sanitized Western industrialized nations.[7][8]
Lack of exposure to naturally occurring pathogens and parasites may result in an increased incidence of autoimmune diseases. This is consistent with the hygiene hypothesis.[3][9] A complete explanation of how environmental factors play a role in autoimmune diseases has still not been proposed. However epidemiological studies, such as the meta analysis by Leonardi-Bee et al.,[3] have helped to establish the link between parasitic infestation and its protective role in autoimmune disease development.
Some recent research appears to confirm that the central tenet of the hygiene hypothesis is true — that parasites, and in particular helminths, have shaped the evolution of at least parts of the human immune system, and even the genes responsible for Crohn's disease, ulcerative colitis and celiac disease — and provides further evidence that it is the absence of parasites, and in particular helminths, that has caused a substantial portion of the increase in incidence of diseases of immune dysregulation and inflammation in industrialized countries in the last century"
further read-
The old friends hypothesis modifies the hygiene hypothesis by proposing that T regulator cells can only become fully effective if they are stimulated by exposure to microorganisms and parasites that have low levels of pathogenicity, and which have coexisted universally with human beings throughout our evolutionary history. This theory has recently been given more credibility by a study demonstrating the impact of infectious organisms, and helminths in particular, upon genes responsible for the production of various cytokines, some involved in the regulation of inflammation, in particular those associated with the development of Crohn's Disease, ulcerative colitis, and celiac disease.[10]
and finally-
The development of vaccines, hygienic practices, and effective medical care have diminished or eliminated the prevalence and impact of many parasitic organisms, as well as bacterial and viral infections. This has been of obvious benefit with the effective eradication of many diseases that have plagued human beings. However, while many severe diseases have been eradicated, humans' exposure to benign and apparently beneficial parasites has also been reduced commensurately. The central thrust of the theory is, therefore, that correct development of T regulator cells in individuals may depend on exposure to organisms such as lactobacilli, various mycobacterium, and helminths.[6] Lack of exposure to sufficient benign antigens, particularly during childhood, is sometimes suggested as a cause of the increase in autoimmune diseases and diseases for which chronic inflammation is a major component in the industrialized world.
In a more simple form what i have picked up from this is- although genetics have a major role in the presences of autoimmune diseases, i believe childhood vaccinations, sanitizers, flu shots, etc. have had an adverse effect on our immune systems because of a lack of need. naturally occuring, human coexisting viruses and bacteria we have immunized ourselves against may actually be the reasoning behind an underdevelopement/dysfunction of regulatory T cells, which are responsible for 'turning off' the immune response initially triggered by foreign bacteria's, antibodies etc. basically you needed these infections etc. to gain full use of your immune system. ever hear the term "use it or lose it"? same idea. we may have immunized ourselves to a point of immobilizing our own immune system and a dysfunction of the immune response regulation has been the outcome.
heres my hypothesis of how to avoid this for generations to come. limit immunization to only severe deadly disease of which is still present in the living area... and not a one size fits all cornucopia immunization of everything known to put at risk mans health. you need to be able to fight off infection yourself. i never get vaccines. (remember im not telling you to do ANY of this. im just giving you something to think about)
the fact that lactobacilli is listed as a lost pathogen/parasite in these studies and have no written connection between that and our (crohns colitis sufferers) suggested dietary ailments/natural remedies, has me pretty convinced that this is not far fetched theory. perhaps reintroducing these "lost" parasites which have symbiotically co-existed with humans since the dawn of time is the answer and perhaps a cure to an uncurable disease =)
now you know how serious i am. thank you for taking the time to read this novel. im currently in the hospital for my crohns and have been doing nothing but researching for the benefit of our alliance. ALOHA~
My researching, as limited as it is, has landed me upon a few things that i feel i should share with those of you who want more than a serious-side-effect-pharmaceutical suppression of the disease, but an understanding of it and how to perhaps naturally combat it.
http://en.wikipedia.org/wiki/Helminthic_therapy
i found this very interesting.Incidence of autoimmune diseases and parasitic infestation
"While it is recognized that there is probably a genetic disposition in certain individuals for the development of autoimmune diseases, the rate of increase in incidence of autoimmune diseases cannot be explained by genetics alone. There is evidence that one of the primary reasons for the increase in autoimmune diseases in the industrialized nations is the significant change in environmental factors over the last century. Environmental factors include exposure to certain artificial chemicals from industrial processes, medicines, farming and food preparation. It is posited that the absence of exposure to certain parasites, bacteria and viruses is playing a significant role in the development of autoimmune diseases in the more sanitized Western industrialized nations.[7][8]
Lack of exposure to naturally occurring pathogens and parasites may result in an increased incidence of autoimmune diseases. This is consistent with the hygiene hypothesis.[3][9] A complete explanation of how environmental factors play a role in autoimmune diseases has still not been proposed. However epidemiological studies, such as the meta analysis by Leonardi-Bee et al.,[3] have helped to establish the link between parasitic infestation and its protective role in autoimmune disease development.
Some recent research appears to confirm that the central tenet of the hygiene hypothesis is true — that parasites, and in particular helminths, have shaped the evolution of at least parts of the human immune system, and even the genes responsible for Crohn's disease, ulcerative colitis and celiac disease — and provides further evidence that it is the absence of parasites, and in particular helminths, that has caused a substantial portion of the increase in incidence of diseases of immune dysregulation and inflammation in industrialized countries in the last century"
further read-
The old friends hypothesis modifies the hygiene hypothesis by proposing that T regulator cells can only become fully effective if they are stimulated by exposure to microorganisms and parasites that have low levels of pathogenicity, and which have coexisted universally with human beings throughout our evolutionary history. This theory has recently been given more credibility by a study demonstrating the impact of infectious organisms, and helminths in particular, upon genes responsible for the production of various cytokines, some involved in the regulation of inflammation, in particular those associated with the development of Crohn's Disease, ulcerative colitis, and celiac disease.[10]
and finally-
The development of vaccines, hygienic practices, and effective medical care have diminished or eliminated the prevalence and impact of many parasitic organisms, as well as bacterial and viral infections. This has been of obvious benefit with the effective eradication of many diseases that have plagued human beings. However, while many severe diseases have been eradicated, humans' exposure to benign and apparently beneficial parasites has also been reduced commensurately. The central thrust of the theory is, therefore, that correct development of T regulator cells in individuals may depend on exposure to organisms such as lactobacilli, various mycobacterium, and helminths.[6] Lack of exposure to sufficient benign antigens, particularly during childhood, is sometimes suggested as a cause of the increase in autoimmune diseases and diseases for which chronic inflammation is a major component in the industrialized world.
In a more simple form what i have picked up from this is- although genetics have a major role in the presences of autoimmune diseases, i believe childhood vaccinations, sanitizers, flu shots, etc. have had an adverse effect on our immune systems because of a lack of need. naturally occuring, human coexisting viruses and bacteria we have immunized ourselves against may actually be the reasoning behind an underdevelopement/dysfunction of regulatory T cells, which are responsible for 'turning off' the immune response initially triggered by foreign bacteria's, antibodies etc. basically you needed these infections etc. to gain full use of your immune system. ever hear the term "use it or lose it"? same idea. we may have immunized ourselves to a point of immobilizing our own immune system and a dysfunction of the immune response regulation has been the outcome.
heres my hypothesis of how to avoid this for generations to come. limit immunization to only severe deadly disease of which is still present in the living area... and not a one size fits all cornucopia immunization of everything known to put at risk mans health. you need to be able to fight off infection yourself. i never get vaccines. (remember im not telling you to do ANY of this. im just giving you something to think about)
the fact that lactobacilli is listed as a lost pathogen/parasite in these studies and have no written connection between that and our (crohns colitis sufferers) suggested dietary ailments/natural remedies, has me pretty convinced that this is not far fetched theory. perhaps reintroducing these "lost" parasites which have symbiotically co-existed with humans since the dawn of time is the answer and perhaps a cure to an uncurable disease =)
now you know how serious i am. thank you for taking the time to read this novel. im currently in the hospital for my crohns and have been doing nothing but researching for the benefit of our alliance. ALOHA~
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