I have UC and have had it for between 15-20 yrs. I only use medicine when I'm flaring, which I am currently. I use Rowasa which is a mesalamine enema. It reduces the inflammation and bleeding. It's the same thing as the other 5-ASA drugs. I am trying these new probiotics since my doctor said they have helped some of his other UC patients. I am just really sensitive to medicines. The Rowasa makes me lose a lot of hair, which really is depressing, but it does stop my bleeding, so it needs to be done. I am hoping that this new probiotic can help me so I can wean off of the medicine. The research looks good, but I guess I will have to try it for at least a month to see if it makes a significant difference. I was hoping that others might have tried it/had success with it. How are you feeling since changing your meds? I hope that you get better quickly!