Question about Prednisone absorption

[jenksed]

In middle of a flair up that pretty much started building up over the last 4 months or so but has gotten extremely bad as of late and ended up with a trip to ER yesterday (due to no insurance). The emergency docs put me on 500mg Flagyl every 6 hours and 50mg Prednisone for 10 days. First I don't think 10 days is enough but I'm hoping to address that at a health department clinic I found yesterday after going to the hospital however I can't make an appt. till Monday.

My question is this. After some D this morning I noticed 2 pills in my D. Both circular and with imprints which tells me it is the Prednisone and not the probiotic pills I am also taking which have no imprint code. Am I getting much of any benefit from this Prednisone if the size of the pills in my D are about the exact same size as the pill before it goes through my system? Should I maybe stop the Flagyl for a few days in hopes that I can hold the Prednisone longer maybe?

Complicating things at the moment is I have a fistula, a hemorrhoid, and a fissure at the moment. It feels like I'm passing razor blades and it's pretty hard for me to hold back anything right now which is also an issue as I can't force myself very well to not go to the bathroom which I would think holding back longer would help the prednisone absorb better if I could keep it in me longer.

Any suggestions or comments anybody????

 

[jenksed]

Is crushing it (GROSS GROSS GROSS just thinking of the taste) and eating in yogurt maybe a possibility? Not sure if it will reach my colon that way and how important it is that it does reach their. I know anti-inflammatory's like Asacol it is important but that's a completely different effect it has. Seems like the systemic effect Pred would have should be enough of a help on my colon.

 

[Jennifer]

I've never crushed Prednisone before but you could contact your pharmacist and ask them. Pharmacies are open on the weekend so you should have no trouble getting an answer. I have no answer for the Flagyl though as I've never been prescribed that for Crohn's.

 

[Rebecca85]

You can get a soluble version of pred, however I guess you would have to wait till Monday. I wouldn't stop the Flagyl, because that's how bacteria develop resistance to antibiotics. In the meantime I would just take the pred, and hope that you absorb enough to tide you over till you can get some soluble pills.

Just had a thought, maybe your stomach isn't acid enough to start dissolving the pills quickly (this is more of a possibility if you take any acid reducing meds). You could try washing the pills down with some orange or cranberry juice to see if that makes a difference.

 

[Mountaingem]

Prednisone affects the adrenal gland, suppressing it so your body won't make extra white cells that cause the inflammation. So I don't think it would matter if you crush them-but YIIIIIIKES the taste!!!!

 

[kossy]

Prednisone comes in a liquid form. That's the way I had to take this lovely medication as a toddler. It does taste nasty, like your sucking on an iron pipe kind of taste. But I did it every morning and night for several years. I don't remember it having an after taste stuck in my mouth, which is a good thing.
I can't take delayed release drugs they just come out the same way the came in and I take gummy vitamins because regular vits pass right through as well.