Hi Mark74!
I have Crohn's which is mainly rectal. They thought I had UC, but a scope found a couple of other patches, so confirmed it as Crohn's, and as far as I know it is only in my colon. I'm currently on oral Pentasa and rectal salofalk, but am waiting for a prescription to start on Mezavant next week. Although very mild, every time I try to cut out the suppositories I start bleeding again, and so I guess the Pentasa isn't getting far enough, and the Mesavant will hopefully do this as it is really aimed at UC which of course starts rectally and spreads upwards. I was told that even though I technically have Crohn's, my actual symptoms are those of UC and so should be treated that way. Fingers crossed.
I was only diagnosed in November and so I have limited knowledge, especially of any other drug groups as I have not needed them (yet!). I'll do my best to answer any questions, but I'm sure there will be others with more experience than me who can help.