This gives a little more credence to LDN which modulates or boosts certain aspects of the immune system.
The side effects of LDN are probably more socially acceptable than the potential side effects of Viagra. On the other hand, I would always have a place to hang my hat.
I think they are over simplifying by saying a weak immune response. I think this is true to an extent but only to the initial immune response. The secondary response seems to be exaggerated because of the weak initial response.
I hardly ever get a bad cold or flu. If I get them at all, there is mild symptoms. My wife will be down and out with the same illness. So will most other people.
I have missed work once in the last ten years with the flu. My wife has missed work because of a high fever from a cold or flu several times in that same period of time. This seems to point to a weak initial response on my part, but in the end, it is eliminated by the secondary response.
To say my immune response is weak would be false by the symptomatic results of a cold or the flu. In the end it seems to work better than average.
The way it works is abnormal. This may even be a way to tell if someone has an auto immune disease by how there immune system responds to common ailments.
This would explain why the approach of weakening the immune system works to an extent. It weakens all of it, which would weaken the secondary immune response. But the real problem is the crappy initial immune response not the compensating secondary response.
This also would explain why stress causes use so much trouble. Stress weakens our initial immune response even more than normal. This causes a extra high secondary immune response to a system already in overdrive.
An analogy would be a prowler out in my yard looking to see if he can get in the house easily. If my initial response is to turn on the outside lights and lock the doors then it is likely nothing more will come of it.
If instead, I load my 308 and wait by the door I may be in for a gun battle. Sure, I may survive the break in, but it could likely result in quite a bit of damage in the process. The secondary response keeps me alive, but it would have been much better for me to have the correct initial response.
OK, enough speculation on that. I certainly could be wrong, but I think it is right enough.
"Honey, could you pick me up some Viagra for my Crohn's?" I don't know if I can pull that one off.
Dan Bergman