Would love to hear from those whove tried both humira and another biologic

[aideen33]

(Back story, im getting nowhere with my current doc and working on the paperwork to see another one in the area soon)

Ive been on Humira since december, after starting Imuran in November. The combo (at the current doses) isnt working well enough to be able to taper the steroids so Im still on those as well since its the only way we've got the bleeding under some level of control,

Current doc said that if Humira didnt work for me then there was no point in trying the other biologics but that seems weird to me.

Anyone been on humira and had it not work, then switched to another biologic with success, or am i holding onto a futile dream

 

[FrozenGirl]

I haven't been on another but my docs is considering a switch if adding methotrexate doesn't help me. That's crazy, you can't lump all the biologics in together. I know some docs if a patient fails an anti TNF drug they don't see a point in trying another ( like my doc didn't feel Humira would help me if Remicade didn't) but there is other types of biologics. Entivyo, Stelara, Cimzia all have different types of action. Some people even fail one TNF drug and have success on another (many go from Remicade to Humira or the other way).

 

[aideen33]

Thats kind of what i thought, its a weird comparison i know but like with anti depressants, even though they may both be say SSRIs just because one SSRI didnt work doesnt mean that another one wont work necessarily.. I feel like writing them all off and coming at it as if "If Humira doesnt work we dont really have any other options besides surgery" is a bit... short sighted to say the least. Thats why Im working on seeing another doc though.. well One of the reasons... just figured id make sure I wasnt totally off base before I go talking to the new one about my options. We still havent tried upping/changing the doses of either Humira or Imuran, nor have we discussed methotrexate, or any other biologic drugs to date

 

[Stepe91]

When I was first diagnosed I was put on Remicade right away. Worked great for about a year before I started developing antibodies against it. Tried Humira next and again it worked until I started developing antibodies again (this time it took 3 years). Now I'm on Cimzia (have been for the past 2 years) and so far its working and no antibodies yet. Every body responds differently to different medications.

 

[rollinstone]

Thats kind of what i thought, its a weird comparison i know but like with anti depressants, even though they may both be say SSRIs just because one SSRI didnt work doesnt mean that another one wont work necessarily.. I feel like writing them all off and coming at it as if "If Humira doesnt work we dont really have any other options besides surgery" is a bit... short sighted to say the least. Thats why Im working on seeing another doc though.. well One of the reasons... just figured id make sure I wasnt totally off base before I go talking to the new one about my options. We still havent tried upping/changing the doses of either Humira or Imuran, nor have we discussed methotrexate, or any other biologic drugs to date

Aideen, please do yourself a favour and contact Dr William Chamberlain, he is actually in Texas which is lucky for you, he prescribes anti-map therapy which actually has higher remission rates than humira. His contact details are on this link. Wishing you all the best.
http://crohnsmapvaccine.com/map-specialists-2/

 

[aideen33]

Oh happy dance, happy dance..... my insurance approved the referral and Dr. Eidem can see me next week!

 

[GABoy]

Hi everyone,

I just saw this thread. I was dx in 2013. I started Humira in early 2014. I thought everything was going well until last month when I was back in surgery. My GI is starting me on Entyvio and 6MP. However, he did not seem overly optimistic about it.