Yeast in vaccines tied to autoimmune diseases

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I don't know the credentials of the people behind the study, but it is clear that the book authors have a vested interest in people reading this and adopting it at face value. When I see such a direct correlation, I tend to adopt a wait and see approach. If there is validity to these findings, others will be able to repeat the results independantly.
 
The reaction to yeast in Crohn's disease is used in the ASCA test which meansure antibodies to Saccharomyces cerevisiae (brewer's yeast)

But that doesn't mean much, since it's not a very specific test to begin with (many hospitals don't use ASCA)...and more importantly, positive ASCA is seen in other disease too, like coeliac and intestinal TB.

In fact, ASCA is so unreliable that it can not differentiate between intestinal TB and crohn's disease: http://www.ncbi.nlm.nih.gov/pubmed/17160471 , nor coeliac http://www.ncbi.nlm.nih.gov/pubmed/21140083 they both can be positive for ASCA, so can a whole bunch of diseases.

Also, unlike coeliac, where the disease improves once you remove the offending agent, crohn's disease and intestinal TB don't get cured once you stop consuming yeast.

The ASCA reaction, if it's not some sort of cross-reaction, I think is just there during flares because of the increased permeability, same reason it's there in intestinal TB I assume. Probably why it's so unreliable.
 
I might have misunderstood the references, but the 1st is saying that the yeast is needed for life
Commensal microorganisms such as Saccharomyces are required for nutrition, proper development of Peyer's aggregated lymphoid tissue, and tissue healing
yet for some reason some people seem to be creating anti bodies to it (not a fault with vaccines)

The last reference seemed to be about how we use the yeast in vaccines and how to exploit new potentials for creating more vaccines!
 

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