Manzyb, I didn't know I was in a flare until I got the results of my colonoscopy back. Then they wanted me to do a pill cam. By the time I got the pill cam results I was having D every day. So since they caught it so early my only symptom this time has been the big D. That is slowly getting better. Next week will be my third set of shots and at this point I am only having D once a day instead of 5 times a day. Slow steady improvement but no overnight success! Sorry to hear you are in so much pain, I hope it kicks in for you soon.