I've been on Humira for a little over 3 months I think. I have the pen now, I started with syringe and I can inject with needles. But the pen is easiest for me. I get joint pain in my lower back and hips. At night time I also lock up and cant turn over, I try and the pain wakes me about and then I need to lever myself up and unlock my back. My bed is new and is a quality bed, so I think its more me than the bed. I get tired, so very very tired. I am happy the crohns is in remission and that is great. I am still coming off the prednisone and I am also on 100mg Azathioprine. I have afternoon naps and I am in bed at 8:30 - 9pm. This week after my *** I lost a lot of hair, had - but I have heaps anyway, also got abdo pain and nausea till midnight. I put on my QV moisturiser for sensitive skin and my face came out in red welts and rash. I washed it off and it settled down. I am sure this is more to do with the Humira than anything else. On a good day I have about 4 hours of energy. But it all beats have active crohns.