I have had Crohn's since 2000 and it was seen in my small intestine at the end and in my rectum. I have had several fistula surgeries before being diagnosed. I take Pentasa 500 mg 2 pills twice a day. For a week, I have have increased loose stools and have developed alot of pressure in my rectum and sitting is becoming uncomfortable. I have upped my Pentasa and have an appt with the dr tomorrow afternoon. Is this a flare and what do you think they will do. I am really nervous because since I have been diagnosed, I have had no problems until now.