Lactulose Enema

[CrowKnee223]

Does anyone have any experience or advice using Lactulose as an enema?

 

[GI Jane]

Nope just soap and plain. Hopefully someone out there can helps.
Cheers.

 

[cmack]

I always swallowed it as directed on the bottle. Never heard of that kind of enema.

Wishing you well,

cmack

 

[cmack]

Pardon me. I may be wrong.

Lactulose
From Wikipedia, the free encyclopedia
Lactulose Lactulose structure.svg
Haworth projection of lactulose.svg
Haworth projection of lactulose (bottom)
Clinical data
Pronunciation /ˈlæktjᵿloʊz/
Trade names Cholac, Generlac, Consulose, Duphalac, others
AHFS/Drugs.com Monograph
MedlinePlus a682338
Pregnancy
category

US: B (No risk in non-human studies)

Routes of
administration By mouth (oral solution)
ATC code A06AD11 (WHO)
Legal status
Legal status

UK: Pharmacy medicines
US: ℞-only

Pharmacokinetic data
Bioavailability Poorly absorbed
Metabolism 100% in colon by enteric bacteria
Onset of action 8 to 48 hours[1][2]
Biological half-life 1.7–2 hours
Excretion Fecal
Identifiers
IUPAC name
[show]
CAS Number 4618-18-2 Yes
PubChem (CID) 11333
DrugBank DB00581 Yes
ChemSpider 10856 Yes
UNII 9U7D5QH5AE Yes
KEGG D00352 Yes
ChEBI CHEBI:6359 Yes
ChEMBL CHEMBL296306 Yes
ECHA InfoCard 100.022.752
Chemical and physical data
Formula C12H22O11
Molar mass 342.296 g/mol
3D model (Jmol) Interactive image
SMILES
[show]
InChI
[show]
(verify)

Lactulose is a non-absorbable sugar used in the treatment of constipation and hepatic encephalopathy.[3][4] It is used by mouth for constipation and either by mouth or in the rectum for hepatic encephalopathy.[3] It generally begins working after eight to twelve hours but may take up to two days to improve constipation.[1][2]

Common side effects include abdominal bloating and cramps. There is the potential for electrolyte problems to occur as a result of diarrhea it produces. No evidence of harm to the baby has been found when used during pregnancy.[3] It is generally regarded as safe during breastfeeding.[5] It is classified as an osmotic laxative.[6]

Lactulose was first made in 1929 and has been used medically since the 1950s.[7][8] It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.[9] It is available as a generic medication.[4] The wholesale price in the developing world is about US$0.18 per dose.[10] In the United States 30 doses of the liquid is about US$20.[3] It is made from the milk sugar lactose and is composed of two simple sugars, galactose and fructose.[11][3]

 

[cmack]

Hope this helps

 

[CrowKnee223]

i have the same information cmack, its repeated over several pages. For rectal enema it suggests 300ml lactulose to 700ml water.

my next question is what water can/should i use?

And GI Jane, what is soap and plain?

thanks

 

[cmack]

Crow,

Not too sure about the water. I'm thinking you should ask a professional. Maybe call a Pharmacist or Doc.

 

[CrowKnee223]

I've tried cmack, they've basically laughed at me. Normal saline seems to be the safest option from my research but when i requested some i was totally disregarded. GI has actually prescribed a supply of enema's, don't know which ones yet as i couldn't read his writing but hoping to get them today. Feels like Christmas morning!!