Questran, aka Cholestryamine, is a powder form. The Crohn's Colitis Foundation Of American had a book written in the '80's. In that, they mentioned that this drug was used to reduce bile acids for Heart Patients. By reducing the bile acids, it helps reduce the absorbtion, consequently reducing Cholesterol. That's why the drug was made, as a Cholesterol lowering drug. Then Crohn's people got word out that it was working for them. Too much bile acid is a huge factor in Crohn's patients with chronic diarrhea.
When I read this, I immediately took the information to my gastroenterologist. He looked at me and said, "Do you know what that drug is for?" I immediately said yes, and that I wanted to at least try it. I got the drug, mixed 1 scoop into a glass of orange juice and after about 2 hours, my diarrhea subsided. I've been on it ever since, and it was around '82 or '83.
There is also a pill form, known as Welchol. I must also say that on the label, it suggests that heart patients take the med after each meal. But, to be aware of the side effects....CONSTIPATION. Yippee, for me. I have over the years used this medicine as needed. If I had more diarrhea, I took another dose of medicine. You can't overdose on the stuff. My cholesterol level is great, by the way.
However, since finding that the Calcium Carbonate works to absorb water,fluids, and food. I'm taking the Calcium 2 -3 times a day and still the Cholestyramine at night. My main problem has always been the build up of acids during the night time.
And, if I stay off of the other type acids, like Dr. Pepper, Root Beer, Lemonades, I do remarkably well.
One other note, the Cholestyramine slows absorbtion. So, you shouldn't take it more than 1 hour before, and more than 2 hours after other medications. I don't take any night medications, so it works well for me.
I even make sure I have it in the hospital. For instance, if I went in for bowel rest with an NG tube. Once the bowel signs returned, they removed the tube, the first thing I did was take Cholestyramine. Because I knew I would then be passing bile acid deluxe, along with the liquid diet. Cholestyramine slowed that down. Heck pre Cholestryramine days, I could just stand up from the bed and poop water and acid.
I would recommend this medication for all Crohn's, Colitis patients with uncontrollable diarrhea. Talk to your Doctors.....