Effects of cholestyramin (questran 4g) on Azathioprine uptake

[Magnus]

Hi guys!

I'm new to the board, but I've had my chron's for around 15 years now (will come with a proper update about me in "your story" later on).

I have a question; does anyone of you know whether the uptake of imuran/azathioprine is negatively affected by questran (cholestyramine)?

I'm afraid that if I take my questran together with my other meds (azathioprine, folic acid, B-12 and iron) it will decrease the effects of them.

Grateful for any replies!

/Magnus

 

[DustyKat]

My daughters GI told us specifically, when she was on Questran, not to take her medications with it but rather to have a 2 hour buffer between Questran and other meds. She was on Imuran (Azathioprine) and Folic Acid at the time.

Dusty.

 

[J28]

My Mum has to leave 4 hours between meds and Questran (3 times a day), a problem fitting everything in especially if she gets something else that is supposed to be taken four times a day.
She takes Azathioprine and waits an hour before taking questran then four hours before the next tablets, has to fit in three times a day.

 

[rob101]

Wtf ! my GI told me nothing about this ....whats the point of putting someone on a heavy drug like Azathioprine when it is not going to be absorbed properly.

 

[J28]

I am sure it either tells you in the box or a leaflet in the box (in the UK anyway).

 

[Magnus]

Thanks for the answers all!

On the leaflet it says that it might have negative effects on some medications, not all then I would presume. I am trying to get a hold of my doctor, but since it always takes a couple of weeks, I thought I'd post here to get some feedback on the matter.