At my infusion center, the main thing spoken about with remi is either exhaustion or lower abdominal pains. It is absolutely a side effect of the drug. Some people didn't feel the pains for the first several doses like you, xoxava. So it's very likely that you are not having a flare. Try to not stress, as you know that will make you worse. I hope you are well and that the pain dies down soon. Good luck.